Acute bronchiolitis

This study tests whether outpatient respiratory physiotherapy can prevent hospitalizations in infants up to 12 months old with mild to moderate acute viral bronchiolitis. The therapy includes gentle airway clearance techniques and, if needed, continuous positive airway pressure (…

This trial tests whether montelukast, a drug used for asthma, can help infants hospitalized with acute bronchiolitis recover faster. About 60 children aged 4 weeks to 2 years will receive either montelukast or a placebo alongside standard care. Researchers will measure changes in…

This study tests whether a nose spray made from treated seawater can shorten the time babies (1 month to 1 year) have symptoms of bronchiolitis, compared to a standard saltwater spray. About 458 infants with their first, mild-to-moderate bout of bronchiolitis will take part. Pare…

This study looks at two ways to end high flow nasal cannula treatment in infants with acute bronchiolitis. One group stops the high flow immediately, while the other gradually reduces it. The goal is to see if immediate stopping shortens hospital stays without causing more breath…

This study looks at two different approaches to help doctors and families avoid unnecessary follow-up visits after a child is hospitalized for bronchiolitis. About 2,700 children will take part to see which method works better at encouraging follow-up only when needed. The goal i…

This study follows 200 infants hospitalized with lower respiratory tract infections (like bronchiolitis) to see if lung ultrasound and special breathing tests can help doctors predict how sick a child will get and who might develop asthma later. Researchers will track symptoms, h…

This study tests whether a two-part approach—improving communication about viral infections and having pharmacists double-check prescription lengths—can reduce how many days antibiotics are prescribed for respiratory infections like bronchitis, sinusitis, and sore throat. About 4…