Could stopping oxygen therapy earlier get bronchiolitis babies home sooner?

NCT ID NCT06321133

Symptom relief Sponsor: Kuopio University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at two ways to end high flow nasal cannula treatment in infants with acute bronchiolitis. One group stops the high flow immediately, while the other gradually reduces it. The goal is to see if immediate stopping shortens hospital stays without causing more breathing problems or readmissions. About 50 infants will take part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: High flow nasal cannula therapy
What this could lead to: If immediate stopping works, it could shorten hospital stays for infants with bronchiolitis, reducing stress on families and hospitals.
What could go wrong: This is a small, early-stage trial with only 50 infants. Immediate stopping might lead to more treatment failures or readmissions, so results may not be widely applicable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2024

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

0 to 12 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinically diagnosed acute bronchiolitis * High flow nasal cannula treatment has lasted for at least 12 hours * Measured saturation 95 or more with room air * High flow rate is maximum 2l/kg/min * The treating doctors considers the infant suitable to be without high flow Exclusion Criteria: * Major congenital anomaly of lungs, hearts or diaphragm * Bacterial pneumonia * Parents do not give consent

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Conditions

The condition(s) this trial relates to.

acute bronchiolitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute bronchiolitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

4 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Could stopping oxygen therapy earlier get bronchiolitis babies home sooner?

What the study statuses mean