Computer-Guided implant surgery aims to rebuild smiles for patients with severe jaw bone loss
NCT ID NCT06129695
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This trial tests two computer-guided surgical methods—intra-sinus versus extra-sinus—for placing zygomatic implants in people whose upper jaw has severely shrunk due to bone loss. Ten patients with atrophic maxillae who cannot use standard implants will receive one of the two approaches. The study measures pain, bone loss around the implant, and complications to determine which method is safer and more effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Zygomatic implants placed via intra-sinus versus extra-sinus surgical approach
- What this could lead to
- If successful, this could identify the safer surgical method for placing zygomatic implants, improving outcomes for patients with severe upper jaw bone loss.
- What could go wrong
- This is a small, early-stage trial with only 10 participants, so results may not apply broadly. Both approaches carry risks like infection or implant failure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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10 people
The number who actually took part.
- Started
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Apr 2023
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients with severely atrophic edentulous upper arch (Cawood class IV, V, VI) that could not be restored by other type of treatment 2. Patients who had at least 8-12 mm vertical bone height in anterior maxilla to allow installation of 2 conventional implants. 3. Lacking posterior maxillary bone support due to significant sinus pneumatistion 4. Good systemic health (ASA score I-II) 5. Highly motivated patients. Exclusion Criteria: 1. Patient not willing to give his/her informed consent. 2. Patients with systemic disease that did not permit the surgical procedure (including general anaesthesia). 3. Patients with uncontrolled diabetes or under bisphosphonate therapy. 4. Heavy smoker.(\> 20 cigarettes daily) 5. Patient with psychiatric problems, severe bruxism or other parafunctional habits. 6. Acute sinusitis. 7. Malignancy or pathology in Maxilla or Zygoma.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentistry, Cairo University
Cairo, 12311, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New implant study aims to restore smiles for those with severe jaw bone loss