Experimental cancer drug ZW171 tested in 32 patients, but study stopped early

NCT ID NCT06523803

First seen Oct 31, 2025 · Last updated Jun 12, 2026 · Updated 34 times

Summary

This early-phase study tested a new drug called ZW171 in 32 people with advanced ovarian, lung, or other cancers that have a protein called mesothelin. The main goals were to check the drug's safety and find the right dose. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Guys and St Thomas' NHS Foundation Trust

    London, SE1 9RT, United Kingdom

  • Icahn School of Medicine at Mount Sinai (ISMMS) - The Blavatnik Family-Chelsea Medical Center

    New York, New York, 10011, United States

  • Norton Cancer Institute

    Louisville, Kentucky, 40202, United States

  • Royal Marsden Hospital

    Sutton, SW3 6JJ, United Kingdom

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • The Catholic University of Korea, Seoul St. Marys Hospital

    Seoul, South Korea

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • Universitaetsklinikum Dresden

    Dresden, 01307, Germany

  • University of Colorado Health Sciences Center

    Aurora, Colorado, 80045, United States

  • University of Southern California - Norris Comprehensive Cancer Center

    Los Angeles, California, 90089, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Yonsei University Health System - Severance Hospital

    Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.