New drug aims to stop dangerous nighttime hypos in type 1 diabetes

NCT ID NCT05762107

Recruiting now Disease control Sponsor: Zucara Therapeutics Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug ZT-01 can reduce nighttime low blood sugar (hypoglycemia) in adults with type 1 diabetes. Participants will inject ZT-01 or a placebo before bed for two 4-week periods while wearing a continuous glucose monitor. The goal is to see if ZT-01 lowers the number of nighttime hypos and to check its safety.

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 1 DIABETES MELLITUS WITH HYPOGLYCEMIA

Contacts and locations

Show contact details

Locations

Albany Medical Center
RECRUITING

Albany, New York, 12203, United States
Atlanta Diabetes Associates
RECRUITING

Atlanta, Georgia, 21044, United States

Contact Email: •••••@•••••
BC Diabetes
RECRUITING

Vancouver, British Columbia, V5Y 3W2, Canada
Baltimore VA Medical Center
RECRUITING

Baltimore, Maryland, 21201, United States
Barbara Davis Center for Diabetes
RECRUITING

Aurora, Colorado, 80045, United States
Centricity Research Barrie Endocrinology
WITHDRAWN

Barrie, Ontario, L4N 7L3, Canada
Centricity Research Calgary Endocrinology
RECRUITING

Calgary, Alberta, T2H 2G4, Canada
Centricity Research Etobicoke Endocrinology
RECRUITING

Etobicoke, Ontario, M9R 4E1, Canada
Centricity Research Toronto
RECRUITING

Toronto, Ontario, M4G 3E8, Canada
Centricity Research Vaughan Endocrinology
RECRUITING

Concord, Ontario, L4K 4M2, Canada
Diabetes & Endocrine Treatment Specialists
RECRUITING

Sandy City, Utah, 84093, United States
Diabetes & Glandular Disease Clinic
RECRUITING

San Antonio, Texas, 78229, United States
East Coast Institute for Research
RECRUITING

Macon, Georgia, 31210, United States
East Coast Institute for Research LLC
RECRUITING

Jacksonville, Florida, 32216, United States
Elite Research Center
RECRUITING

Flint, Michigan, 48532, United States
Hanson Diabetes Center
RECRUITING

Port Charlotte, Florida, 33952, United States
Headlands Research
RECRUITING

Escondido, California, 92025, United States
IU Health University Hospital
RECRUITING

Indianapolis, Indiana, 46202, United States
Kirklin Clinic of UAB Hospital-Endocrinology/Diabetes Clinic
RECRUITING

Birmingham, Alabama, 35233, United States
LCGK Research
TERMINATED

San Carlos, California, 94070, United States
Lucas Research Inc.
RECRUITING

Morehead City, North Carolina, 28557, United States
MedStar Good Samaritan Hospital
RECRUITING

Baltimore, Maryland, 21239, United States
Medical Investigations Indications Inc.
RECRUITING

Little Rock, Arkansas, 72211, United States
Metabolic Research Institute
RECRUITING

West Palm Beach, Florida, 33401, United States
Mount Sinai Hospital: Leadership Sinai Centre for Diabetes
RECRUITING

Toronto, Ontario, M5T 3L9, Canada
NYC Research Inc.
RECRUITING

Long Island City, New York, 11106, United States
NYU Langone Health CTSI
RECRUITING

New York, New York, 10016, United States
North Texas Endocrine Center
RECRUITING

Dallas, Texas, 75231, United States
Ochsner Clinic Foundation
RECRUITING

New Orleans, Louisiana, 70121, United States
Ohio State University Wexner Medical Center
RECRUITING

Columbia, Ohio, 43210, United States
Palm Research Center, Inc.
RECRUITING

Las Vegas, Nevada, 89148, United States

Contact Email: •••••@•••••
Physicians Research Associates LLC
RECRUITING

Lawrenceville, Georgia, 30046, United States
Richmond Road Diagnostic & Treatment Centre, Clinical Trials Unit
RECRUITING

Calgary, Alberta, T2T5C7, Canada
Southern Endocrinology Associates
RECRUITING

Mesquite, Texas, 75149, United States
Suncoast Clinical Research
RECRUITING

New Port Richey, Florida, 34652, United States
Texas Diabetes & Endocrinology, PA
RECRUITING

Austin, Texas, 78749, United States
Thomas Jefferson University
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
UPMC Presbyterian Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
USC Keck Medicine Eastside Center for Diabetes
RECRUITING

Los Angeles, California, 90022, United States
University Diabetes & Endocrine Consultants
RECRUITING

Chattanooga, Tennessee, 37411, United States
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of South Florida Diabetes & Endocrinology Clinic
RECRUITING

Tampa, Florida, 33612, United States
University of Washington Diabetes Institute - Clinical Research Unit
RECRUITING

Seattle, Washington, 98109, United States
Yale University - Diabetes Research Office
RECRUITING

New Haven, Connecticut, 06511, United States

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