New shot could help teens with rare, severe high cholesterol

NCT ID NCT07473843

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called zodasiran in 12 teens aged 12 to 17 with homozygous familial hypercholesterolemia, a rare genetic condition causing very high cholesterol. The drug is given as a shot under the skin. The main goal is to see if it safely lowers bad cholesterol after 12 months. Participants must already be on other cholesterol-lowering treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Congenital, Hereditary, and Neonatal Diseases and Abnormalities Dyslipidemias hereditary disease homozygous familial hypercholesterolemia hyperlipidemia hyperlipoproteinemia Hyperlipoproteinemia Type II inborn errors of metabolism Lipid Metabolism Disorders Lipid Metabolism, Inborn Errors metabolic disease Nutritional and Metabolic Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••