Drug trial aims to tame dangerous lupus kidney disease

NCT ID NCT05781750

Terminated Disease control Sponsor: Kezar Life Sciences, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether a new drug, zetomipzomib, could help control active lupus nephritis, a serious kidney disease caused by lupus. About 84 patients received either the drug or a placebo as a weekly injection for a year, in addition to their standard care. The main goal was to see if the drug could improve kidney function and reduce protein in the urine more effectively than standard treatment alone.

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Contacts and locations

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Locations

Accurate Clinical Research - Lake Charles

Lake Charles, Louisiana, 70605, United States
All India Institute of Medical Sciences

Raipur, Chhattisgarh, 492099, India
Aprillus Assistance and Research by Arcis Health

Buenos Aires, C1406AGA, Argentina
Assured Care Plus Hospital

Nashik, Maharashtra, 422101, India
Austral University Hospital

Pilar, B1629ODT, Argentina
Center for Advanced Health Clinical Studies

Guatemala City, 01009, Guatemala
Clinical Hospital FMUSP

São Paulo, 05403-000, Brazil
Clinical Research Center, S.A.

Guatemala City, 01010, Guatemala
Clinics Hospital FMRP

Ribeirão Preto, São Paulo, 14051-140, Brazil
Costa Clinica

Barranquilla, Atlántico, 080020, Colombia
Dr. Doreski Medical Offices

Buenos Aires, C1426ABP, Argentina
Elite Mission Hospital

Thrissur, Kerala, 680007, India
Faculty of Medicine of SJRP

São José do Rio Preto, São Paulo, 15090-000, Brazil
Far Eastern University Hospital Nicanor Reyes Medical Foundation

Quezon City, National Capital Region, 1118, Philippines
Framingham Medical Center

Buenos Aires, B1902ADW, Argentina
Guangdong Provincial People's Hospital

Guangzhou, Guangdong, 510080, China
Holy House of Mercy of Belo Horizonte

Belo Horizonte, Minas Gerais, 30150-221, Brazil
Hospital Raja Permaisuri Bainun

Ipoh, Perak, 30450, Malaysia
Hospital Selayang

Batu Caves, Selangor, 68100, Malaysia
Hospital Sultan Idris Shah Serdang

Kajang, Selangor, 43000, Malaysia
Iloilo Doctors' Hospital

Iloilo City, Iloilo, 5000, Philippines
Jasleen Hospital

Nagpur, Maharashtra, 440012, India
Kingsway Hospital

Nagpur, Maharashtra, 440001, India
Krishna Institute of Medical Science

Secunderabad, Telangana, 500003, India
Laiko General Hospital of Athens

Athens, 11527, Greece
MGM Medical College and Hospital

Aurangabad, Maharashtra, 431003, India
ManilaMed - Medical Center Manila

Manila, National Capital Region, 1000, Philippines
Mary Mediatrix Medical Center

Lipa City, Batangas, 4217, Philippines
Mayo Clinic of UCMB SRL

San Miguel de Tucumán, Tucumán Province, T4000, Argentina
Medical Clinic Specialized in Internal Medicine and Rheumatology

Guatemala City, 01010, Guatemala
Medical Clinic Specialized in Internal Medicine and Rheumatology

Guatemala City, 01011, Guatemala
Medical Research Organization

Buenos Aires, C1015, Argentina
Military Central Hospital

Buenos Aires, C1426BOS, Argentina
Nephrology Associates, Inc

East Providence, Rhode Island, 02914, United States
Nirmal Hospital

Surat, Guajrat, 395002, India
Panchshil Hospital

Ahmedabad, Gujarat, 380005, India
Peking University Shenzhen Hospital

Shenzhen, Guangdong, 518036, China
Phoenix Pharma

Port Elizabeth, Eastern Cape, 6001, South Africa
Precision Comprehensive Clinical Research Solutions

Colleyville, Texas, 76034, United States
Prince Court Medical Centre

Kuala Lumpur, Kuala Lumpur, 50450, Malaysia
Prolato Clinical Research Center (PCRC)

Houston, Texas, 77054, United States
SMS Medical College

Jaipur, Rajasthan, 302001, India
Sir Ganga Ram Hospital

New Delhi, NCT of Delhi, 110060, India
St. Luke's Medical Center

Quezon City, National Capital Region, 1102, Philippines
The Catholic University of Korea, Seoul St. Mary's Hospital

Seoul, 06591, South Korea
Unity Hospital

Surat, Guajrat, 395010, India
University Malaya Medical Centre

Kuala Lumpur, 59100, Malaysia
University of Santo Tomas Hospital

Manila, 1015, Philippines
Yashoda Hospitals

Hyderabad, Telangana, India, India
Zhujiang Hospital of Southern Medical University

Guangzhou, Guangdong, 510280, China

Conditions

Explore the condition pages connected to this study.

LUPUS NEPHRITIS