New drug could reverse liver damage in MASH patients
NCT ID NCT07221227
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times
Summary
This study tests a new medicine called efimosfermin alfa in 1200 adults with MASH (a type of fatty liver disease) and moderate-to-severe liver scarring. The goal is to see if the drug can improve scarring and reduce liver inflammation without making the disease worse. Participants will receive either the drug or a placebo, and their liver health will be monitored for about a year.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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GSK Investigational Site
RECRUITINGArcadia, California, 91006, United States
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GSK Investigational Site
RECRUITINGCovina, California, 91723, United States
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GSK Investigational Site
RECRUITINGLos Angeles, California, 90057, United States
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GSK Investigational Site
RECRUITINGSanta Maria, California, 93458, United States
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GSK Investigational Site
RECRUITINGVan Nuys, California, 91405, United States
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GSK Investigational Site
RECRUITINGBoynton Beach, Florida, 33435, United States
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GSK Investigational Site
RECRUITINGCape Coral, Florida, 33914, United States
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GSK Investigational Site
RECRUITINGHialeah, Florida, 33016, United States
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GSK Investigational Site
RECRUITINGHialeah, Florida, 33016, United States
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GSK Investigational Site
RECRUITINGInverness, Florida, 34452, United States
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GSK Investigational Site
RECRUITINGJacksonville, Florida, 32216, United States
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GSK Investigational Site
RECRUITINGKissimmee, Florida, 34744, United States
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GSK Investigational Site
RECRUITINGLakeland, Florida, 33803, United States
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GSK Investigational Site
RECRUITINGMaitland, Florida, 32751, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33135, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33144, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33155, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33156, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33184, United States
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GSK Investigational Site
RECRUITINGMiami Lakes, Florida, 33014, United States
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GSK Investigational Site
RECRUITINGOcala, Florida, 34471, United States
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GSK Investigational Site
RECRUITINGPalmetto Bay, Florida, 33157, United States
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GSK Investigational Site
RECRUITINGTopeka, Kansas, 66606, United States
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GSK Investigational Site
RECRUITINGSpringfield, Missouri, 62703, United States
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GSK Investigational Site
RECRUITINGSt Louis, Missouri, 63141, United States
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GSK Investigational Site
RECRUITINGEast Syracuse, New York, 13057, United States
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GSK Investigational Site
RECRUITINGNew York, New York, 10036, United States
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GSK Investigational Site
RECRUITINGNew York, New York, 10036, United States
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GSK Investigational Site
RECRUITINGMorehead City, North Carolina, 28557, United States
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GSK Investigational Site
RECRUITINGAkron, Ohio, 44320, United States
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GSK Investigational Site
RECRUITINGSpringboro, Ohio, 45066, United States
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GSK Investigational Site
RECRUITINGChattanooga, Tennessee, 37421, United States
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GSK Investigational Site
RECRUITINGAustin, Texas, 78704, United States
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GSK Investigational Site
RECRUITINGAustin, Texas, 78759, United States
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GSK Investigational Site
RECRUITINGBellaire, Texas, 77401, United States
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GSK Investigational Site
RECRUITINGBrownsville, Texas, 78526, United States
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GSK Investigational Site
RECRUITINGDallas, Texas, 75243, United States
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GSK Investigational Site
RECRUITINGDeSoto, Texas, 75115, United States
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GSK Investigational Site
RECRUITINGRichmond, Texas, 77406, United States
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GSK Investigational Site
RECRUITINGSan Antonio, Texas, 78215, United States
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GSK Investigational Site
RECRUITINGSan Antonio, Texas, 78229, United States
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GSK Investigational Site
RECRUITINGSeabrook, Texas, 77586, United States
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GSK Investigational Site
RECRUITINGSugar Land, Texas, 77479, United States
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GSK Investigational Site
RECRUITINGTomball, Texas, 77375, United States
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GSK Investigational Site
RECRUITINGWaco, Texas, 76710, United States
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GSK Investigational Site
RECRUITINGWaco, Texas, 76712, United States
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GSK Investigational Site
RECRUITINGWest Jordan, Utah, 84088, United States
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GSK Investigational Site
RECRUITINGManassas, Virginia, 20110, United States
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GSK Investigational Site
RECRUITINGSeattle, Washington, 98105, United States
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