New drug trial targets rare nasal cancer

NCT ID NCT07527169

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This phase 2 study tests the drug zanzalintinib in 16 adults with recurrent or metastatic olfactory neuroblastoma, a rare cancer of the nasal cavity. The goal is to see if the drug can help control the disease and to check its safety. Participants must not have had prior treatment with similar drugs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
zanzalintinib (a drug taken orally that targets blood vessel growth in tumors)
What this could lead to
If it works, this could offer a new treatment option to control recurrent or metastatic olfactory neuroblastoma, a rare cancer.
What could go wrong
This is a small, early-phase trial with only 16 participants, so results may not apply broadly. The drug may cause side effects or fail to control the cancer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

esthesioneuroblastoma Esthesioneuroblastoma, Olfactory

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UT MD Anderson

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.