New hope for liver cancer: adding zanzalintinib to standard therapy

NCT ID NCT07226063

First seen Nov 11, 2025 · Last updated May 25, 2026 · Updated 23 times

Summary

This study is for people with advanced liver cancer who have already received two immunotherapy drugs (tremelimumab and durvalumab) and are now on durvalumab alone. Participants will add an experimental drug called zanzalintinib to their durvalumab treatment. The goal is to see if this combination helps them live longer without their cancer growing. About 16 adults will take part in this Phase 2 trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44106, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.