New painkiller aims to ease suffering after abdominal surgery
NCT ID NCT06680466
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests a new drug called YZJ-4729 for people experiencing moderate to severe pain after abdominal surgery. Participants are randomly assigned to receive one of several doses of YZJ-4729, a placebo, or the standard painkiller morphine. The goal is to see how well YZJ-4729 relieves pain over 24 hours and to check for any side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
YZJ-4729
What this could lead to
If successful, YZJ-4729 could offer a new option for managing acute pain after surgery with potentially fewer side effects than morphine.
What could go wrong
This is an early-phase trial with a small number of participants, so results may not apply broadly. The drug may not prove more effective or safer than existing treatments.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Third Xiangya Hospital of Central South University
Changsha, Hunan, China