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Yoga may offer Drug-Free relief for severe headaches

NCT ID NCT07348783

Symptom relief Sponsor: Karolinska Institutet Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 30, 2026 · Updated 3 times

Summary

This study tests whether doing yoga-based exercises once a week for 8-12 weeks can reduce headache frequency and improve sleep and quality of life in people with chronic migraine or cluster headache. Participants can join online or in person. The goal is to see if yoga can be a helpful add-on to standard care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
yoga-based exercises
What this could lead to
If it works, this could offer a low-risk, drug-free way to reduce headache frequency and improve sleep and well-being for people with chronic migraine or cluster headache.
What could go wrong
This is a small, early-stage study with only 80 participants. The effect may be small or not work for everyone, and results may not apply to all headache types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed chronic migraine and/or cluster (Hortons) headache * Men and women 18-65 years * Diagnosed with chronic/high frequency migraine (≥15 headache days/month with at least ≥8 with migraine) * Diagnosed with chronic cluster head ache (i.e shorter remission than 3 months per year), diagnosed according to ICHD-III criteria. * Ability to perform yoga based moments and to give consent. * Internet connection with computer/ipad/mobile to perform digitally/tele-health instructions * Willing to use wristwatch for actigraphy * Willing to leave blood samples in laboratory Exclusion Criteria: * Recent or planned operations during the last 6 weeks * Drug dependence, alcohol dependence, mental disorders as psychosis, bipolar disorder, anxiety as PTSD etc) * Parallel enrollment in other clinical trails * Unmedicated high blood pressure, heart disease as heart failure * Non Swedish speaking * Not able to perform low intensity exercise at home or FTF (face to face) - both online or live. * Participants unsure to participate due to drug addiction or other causes * Disorientation and not able to inform regarding other serious conditions

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome cluster headache syndrome migraine disorder trigeminal autonomic cephalalgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cluster headache - episodic and chronic Cluster headaches and other trigeminal autonomic cephalgias Migraine disorder Migraine headache Migraine headache, with or without aura Migraine in adults

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Karolinska Institutet

    RECRUITING

    Huddinge, 141 83, Sweden

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