New drug YK012 tested in early leukemia trial

NCT ID NCT06580301

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial is testing a new drug called YK012 in 46 people with B-cell acute lymphoblastic leukemia (B-ALL). The main goals are to check the drug's safety, find the right dose, and see if it shows any signs of fighting the cancer. Participants will receive YK012 through several cycles of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

YK012 (a drug given by injection)

What this could lead to

If it works, this could point toward a treatment for B-cell acute lymphoblastic leukemia that helps control the disease.

What could go wrong

This is a very early, small trial (Phase 1/2) with only 46 people. It mainly checks safety and dosing, not whether the drug works well. Side effects are possible, and the drug may not be effective.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia Burkitt lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Zhongshan Hospital of Dalian University

    RECRUITING

    Dalian, Liaoning, 116001, China

    Contact

    Contact

  • Guangdong Provincial People's Hospital

    RECRUITING

    Guangzhou, Guangdong, 510080, China

    Contact

  • Henan Provincial People's Hospital

    RECRUITING

    Zhengzhou, Henan, 450003, China

    Contact

  • Shengjing Hospital of China Medical University

    RECRUITING

    Shenyang, Liaoning, 110000, China

    Contact

  • Sun Yat-sen Memorial Hospital

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact

  • The Affiliated Hospital of Guizhou Medical University

    RECRUITING

    Guiyang, Guizhou, 550004, China

    Contact

  • The Affiliated Hospital of Xuzhou Medical University

    RECRUITING

    Xuzhou, Jiangsu, 221000, China

    Contact

  • The First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130021, China

    Contact

  • The Second Affiliated Hospital of Kunming Medical University

    RECRUITING

    Kunming, Yunnan, 650033, China

    Contact