New hope for toddlers with sickle cell: drug may stop painful attacks
NCT ID NCT06923111
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a liquid medicine called Xromi (hydroxycarbamide) can safely prevent painful complications of sickle cell disease in children aged 9 months to 2 years. About 180 children will take part, with some receiving Xromi and a comparison group of similar children who did not get the drug. Researchers will track side effects and how well the medicine works over 2 years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Basildon University Hospital
RECRUITINGBasildon, United Kingdom
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Evelina London Children's Hospital
RECRUITINGLondon, United Kingdom
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John Radcliffe Hospital
RECRUITINGOxford, United Kingdom
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Kings College Hospital
RECRUITINGLondon, United Kingdom
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Noah's Ark Children's Hospital for Wales
RECRUITINGCardiff, United Kingdom
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North Middlesex University Hospital
RECRUITINGLondon, United Kingdom
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Royal Manchester Children's Hospital
RECRUITINGManchester, United Kingdom
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The Royal London Hospital
RECRUITINGLondon, United Kingdom
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University College London Hospital
RECRUITINGLondon, United Kingdom
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Universitätsklinikum Hamburg-Eppendorf
RECRUITINGHamburg, Germany
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Universitätsklinikum Heidelberg
RECRUITINGHeidelberg, Germany
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Whittington Hospital
RECRUITINGLondon, United Kingdom