New combo tackles Hard-to-Treat myeloma

NCT ID NCT05646836

First seen Nov 17, 2025 · Last updated Jun 17, 2026 · Updated 19 times

Summary

This early-phase study tests a new drug (XmAb24306) combined with another drug (cevostamab) in people with multiple myeloma that has come back or stopped responding to at least three prior treatments. The main goal is to check safety and find the right dose. About 90 participants will take part, and researchers will also monitor how well the drugs work against the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • Asan Medical Center - PPDS

    Seoul, 05505, South Korea

  • Clinica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

  • Evangelismos General Hospital of Athens

    Athens, 106 76, Greece

  • Hospital Universitari i Politecnic La Fe de Valencia

    Valencia, 46026, Spain

  • Oslo University Hospital Rikshospitalet

    Oslo, N - 0424, Norway

  • Peter Maccallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Rabin Medical Center-Beilinson Campus

    Petah Tikva, 4941492, Israel

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

  • Severance Hospital, Yonsei University

    Seoul, 03722, South Korea

  • Sygehus Lillebaelt - Vejle Sygehus

    Vejle, 7100, Denmark

  • Tel Aviv Sourasky Medical Center PPDS

    Tel Aviv, 64239, Israel

  • University of Athens, Hematological Clinic,

    Athens, 115 28, Greece

Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.