New pill hopes to stall prostate cancer when other treatments stop working
NCT ID NCT06568562
First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 3 times
Summary
This phase 2 study tests an oral drug called XL092 (Zanzalintinib) in 32 men with metastatic castration-resistant prostate cancer that has worsened after treatment with Lu-PSMA-617. Participants take one tablet daily at home. The main goal is to see how many men have their cancer stop growing after 16 weeks. Researchers will also monitor side effects and how well the drug works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
XL092 (Zanzalintinib) tablet taken once daily by mouth
What this could lead to
If it works, this could offer a new oral treatment option for men with advanced prostate cancer who have stopped responding to a previous therapy.
What could go wrong
This is a small, early-phase study with only 32 participants, so results may not apply to everyone. The drug may cause side effects or fail to control the cancer.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Huntsman Cancer Institute at University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••