New hope for lung cancer patients with stubborn mutation
NCT ID NCT06868485
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests an experimental oral drug called WSD0922-FU in 40 adults with advanced non-small cell lung cancer that has a specific mutation (C797S) and has stopped responding to the standard treatment osimertinib. The main goal is to see if the drug can shrink tumors. It is an early-stage trial, so success is not guaranteed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
WSD0922-FU (an oral drug targeting a specific lung cancer mutation)
What this could lead to
If it works, this could offer a new treatment option for people with a specific type of lung cancer that has stopped responding to current therapy.
What could go wrong
This is an early Phase 2 trial with only 40 participants, so results may not apply to everyone. The drug may not shrink tumors or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Bordeaux - Centre Francois Magendie
RECRUITINGPessac, New Aquitaine, 33604, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Toulon - Hopital Sainte Musse
RECRUITINGToulon, Var, 83100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Francois Baclesse
RECRUITINGCaen, Normandy, 14000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Hospitalier Universitaire (CHU) de Rennes - Hopital de Pontchaillou
RECRUITINGRennes, Ille-et-Vilaine, 35000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Hospitalier Universitaire CHU De Limoges
RECRUITINGLimoges, New Aquitaine, 87042, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic Weston Hospital
RECRUITINGWeston, Florida, 33331, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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FOMAT Oncology
RECRUITINGOxnard, California, 93030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fujian Provincial Cancer Hospital
RECRUITINGFuzhou, Fujian, 350014, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hackensack Meridian Health-Southern Ocean Medical Center
RECRUITINGManahawkin, New Jersey, 08050, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai East hospital
RECRUITINGShanghai, Shanghai Municipality, 200120, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai Pulmonary Hospital
RECRUITINGShanghai, Shanghai Municipality, 200433, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tianjin Medical University Cancer Institute and Hospital
RECRUITINGTianjin, Tianjin Municipality, 300202, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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TxO Central/South, Texas Oncology -Central/South Texas
RECRUITINGAustin, Texas, 78745, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15235, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Virginia Cancer Specialists
RECRUITINGFairfax, Virginia, 22031, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wuhan Union Hospital
RECRUITINGWuhan, Hubei, 430022, China
Contact Phone: •••-•••-•••• Email: •••••@•••••