New hope for lung cancer patients whose tumors outsmart frontline therapy

NCT ID NCT06868485

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tests a new drug, WSD0922-FU, in 40 adults with advanced non-small cell lung cancer that has a specific genetic change (C797S mutation) and has stopped responding to the standard first treatment, osimertinib. The main goal is to see how many patients' tumors shrink or disappear. This is an early-phase trial, so the drug's safety and effectiveness are still being evaluated.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Bordeaux - Centre Francois Magendie

    RECRUITING

    Pessac, New Aquitaine, 33604, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Toulon - Hopital Sainte Musse

    RECRUITING

    Toulon, Var, 83100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Francois Baclesse

    RECRUITING

    Caen, Normandy, 14000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire (CHU) de Rennes - Hopital de Pontchaillou

    RECRUITING

    Rennes, Ille-et-Vilaine, 35000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire CHU De Limoges

    RECRUITING

    Limoges, New Aquitaine, 87042, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic Weston Hospital

    RECRUITING

    Weston, Florida, 33331, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • FOMAT Oncology

    RECRUITING

    Oxnard, California, 93030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fujian Provincial Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, 350014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hackensack Meridian Health-Southern Ocean Medical Center

    RECRUITING

    Manahawkin, New Jersey, 08050, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Karmanos Cancer Institute

    RECRUITING

    Detroit, Michigan, 48201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai East hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200120, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai Pulmonary Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200433, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University Cancer Institute and Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300202, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • TxO Central/South, Texas Oncology -Central/South Texas

    RECRUITING

    Austin, Texas, 78745, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Virginia Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wuhan Union Hospital

    RECRUITING

    Wuhan, Hubei, 430022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.