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Closing wounds later may cut infection risk after belly surgery

NCT ID NCT07531576

Disease control Sponsor: Ayub Teaching Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 78 patients who had emergency abdominal surgery for serious infections. Doctors compared closing the wound right away versus leaving it open for a few days to drain before closing. The goal was to see which method leads to fewer infections and wound problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

78 people

The number who actually took part.

Started

Feb 2021

Finished

Jun 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria To be included in the study, patients had to meet all of the following requirements: Free intraperitoneal contamination resulting from the perforation of any hollow viscus, abdominal trauma, or firearm injuries . Both genders were eligible for participation . Participants had to fall within the age group of 15 to 80 years . Exclusion Criteria Patients meeting any of the following conditions were excluded from the trial to ensure the integrity of the results and control for confounding variables: Age: Anyone younger than 15 years of age . Pregnancy: All pregnant women were excluded . Type of Surgery: Patients undergoing elective (scheduled) laparotomy rather than emergency procedures . Medication: Any patient currently using steroids for any medical issue . Specific Medical Conditions: Peritonitis caused specifically by pancreatitis . Diabetes mellitus, which was excluded to regulate factors that interfere with wound healing . Individuals with compromised immune systems . These criteria were established to limit the progression of infection and specifically evaluate the impact of the wound closure technique-primary closure versus delayed primary closure-without the interference of significant comorbidities or external factors like malnutrition and immune suppression .

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Conditions

The condition(s) this trial relates to.

peritonitis Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delayed primary closure Peritonitis Primary closure

Contacts and locations

Locations

  • Ayub Teaching Hospitql

    Abbottabad, KPK, 22010, Pakistan

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