Taiwan study hunts for hidden genetic clues in rare stomach cancer

NCT ID NCT04821895

Ongoing Knowledge-focused Sponsor: National Health Research Institutes, Taiwan Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study looks at the genetic makeup of a rare stomach cancer called gastrointestinal stromal tumor (GIST) in patients whose tumors lack common mutations. Researchers will analyze tumor samples from 50 people in Taiwan to find other genetic changes that might be treatable. The goal is to understand why some GISTs don't respond to standard drugs and to discover new treatment options.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could reveal new genetic targets for treating wild type GIST, potentially leading to better therapies for this rare cancer.
What could go wrong: This is a small, early-stage observational study, not a treatment trial. It may not identify actionable genetic changes, and any findings would need further research to confirm.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastrointestinal stromal tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROINTESTINAL STROMAL TUMOR (GIST)

Contacts and locations

Locations

Chang Gung Memorial Hospital

Kaohsiung City, Taiwan
Chang Gung Memorial Hospital

Taoyuan, Taiwan
China Medical University Hospital

Taichung, Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, Taiwan
Kaohsiung Veterans General Hospital

Kaohsiung City, Taiwan
Mackay Memorial Hospital

Taipei, Taiwan
National Cheng Kung University Hospital

Tainan, Taiwan
National Taiwan University Hospital

Taipei, Taiwan
Taichung Veterans General Hospital

Taichung, Taiwan
Taipei Veterans General Hospital

Taipei, Taiwan
Tri-Service General Hospital

Taipei, Taiwan

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