Teen obesity study: does shedding pounds boost Post-Meal calorie burn?
NCT ID NCT07400159
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how weight loss affects the energy the body uses to digest food (called dietary thermogenesis) in teens with obesity. Researchers will compare 30 obese adolescents before and after weight loss with normal-weight teens. The goal is to understand if losing weight helps improve this calorie-burning process, which may play a role in managing obesity.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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11 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: • Adolescents aged 11 to 17 (inclusive), at Tanner stage 3-5 of sexual maturation, * With obesity defined by a Quételet index above the 97th percentile according to national curves for adolescents with obesity and a Quételet index classifying them as normal weight adolescents for the control group, * Adolescents affiliated with the social security system or equivalent, * Adolescent who has been informed and has given written consent to participate in the study. Exclusion Criteria: • Refusal to participate in the study, * Refusal of consent by legal guardians, * Regular consumption of tobacco or alcohol, * Special diet, * Participation in regular and intense physical and sporting activities, * Medical or surgical history deemed by the investigator to be incompatible with the study, * Presence of diabetes, and any other condition limiting the application of either strategy being tested, * Adolescents undergoing energy restriction or a weight loss program through physical activity at the time of inclusion or during the last 6 months, * Taking medication that may interfere with the study results. * Adolescents with cardiovascular problems, i.e., subjects with a history of cardiovascular and/or neurovascular disease, as well as subjects with cardiovascular and/or neurovascular risk factors (excluding obesity/overweight). * Surgery in the previous 3 months, * Adolescents who are currently excluded from another study, * Pregnant or breastfeeding adolescents, * Adolescents under guardianship/curatorship or legal protection, * Parents under guardianship/curatorship or legal protection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Laboratoire AME2P, Université Clermont Auvergne
Aubière, 63170, France
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