Weekly shot could shed pounds and quiet sleep apnea

NCT ID NCT07571109

Recruiting now Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

First seen May 16, 2026 · Last updated May 24, 2026 · Updated 2 times

Summary

This study tests a new once-weekly injection, NNC0487-0111, in 300 adults who are overweight or have obesity and also have moderate-to-severe obstructive sleep apnea treated with a breathing machine. Participants are randomly assigned to receive either the study drug or a placebo for about one year. The main goals are to see how much weight people lose and whether their sleep apnea improves, measured by breathing pauses per hour.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

4 Wojskowy Szpital Kliniczny Z Poliklinika Samodzielny Publiczny Zaklad Opieki Zdrowotnej We Wroclawiu
NOT_YET_RECRUITING

Wroclaw, Dolnoslaskie Voivodeship, 50-981, Poland
5 Wojskowy Szpital Kliniczny z Polikliniką-Samodzielny Publiczny Zakład Opieki Zdrowotnej w Krakowie
NOT_YET_RECRUITING

Krakow, 30-901, Poland
Adana Şehir Eğitim ve Araştırma Hastanesi-Dahiliye
RECRUITING

Yuregir/Adana, 01060, Turkey (Türkiye)
Advanced Neurology Epilepsy and Sleep Center ANESC
RECRUITING

El Paso, Texas, 79912, United States
All India Institute of Medical Sciences (AIIMS), Bhubaneswar
NOT_YET_RECRUITING

Bhubaneswar, Odisha, 751019, India
All India Institute of Medical Sciences_Delhi
NOT_YET_RECRUITING

Delhi, New Delhi, 110029, India
Amrita Institute Of Medical Sciences & Research Centre
NOT_YET_RECRUITING

Kochi, Kerala, 682041, India
Ankara Etlik Şehir Hastanesi-Göğüs Hastalıkları
RECRUITING

Yenimahalle / Ankara, 06170, Turkey (Türkiye)
Apollo Multispeciality Hospital, Kolkata
NOT_YET_RECRUITING

Kolkata, West Bengal, 700054, India
Asian Kidney Hospital And Medical Centre
NOT_YET_RECRUITING

Nagpur, Maharashtra, 440010, India
Asthma Bhawan
NOT_YET_RECRUITING

Jaipur, 302039, India
Bhaktivedanta Hospital & Research Institute
NOT_YET_RECRUITING

Mumbai, Maharashtra, 401107, India
Biorhythms Center for Integrative Sleep Medicine
RECRUITING

El Paso, Texas, 79912, United States
Bogan Sleep Consultants, LLC
RECRUITING

Columbia, South Carolina, 29201, United States
Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi-Göğüs Hastalıkları
RECRUITING

Yıldırım/Bursa, 16310, Turkey (Türkiye)
CTI Clinical Research Center
RECRUITING

Cincinnati, Ohio, 45212, United States
Cathay General Hospital
NOT_YET_RECRUITING

Taipei, 106, Taiwan
Centrum Badan Klinicznych PI-House Sp. z o.o.
NOT_YET_RECRUITING

Gdansk, 80-546, Poland
Chang Gung Memorial Hospital, Linkou
NOT_YET_RECRUITING

Taoyuan, 333, Taiwan
Chatani NeuroSleep Clinic_Neurology
RECRUITING

Hiroshima, 730-0051, Japan
Chicago Research Center, Inc
RECRUITING

Chicago, Illinois, 60634, United States
Chutoen General Medical Center_Neurology
NOT_YET_RECRUITING

Shizuoka, 436-8555, Japan
Clinical Research Associates of Central PA, LLC
NOT_YET_RECRUITING

DuBois, Pennsylvania, 15801, United States
DM Clinical
RECRUITING

Bradenton, Florida, 34209, United States
Dignity Health, Mercy Gilbert
RECRUITING

Gilbert, Arizona, 85297, United States
Ditmanson Medical Foundation Chia-Yi Christian Hospital
NOT_YET_RECRUITING

Chiayi City, 600, Taiwan
ETG Warszawa Sp. z o.o.
NOT_YET_RECRUITING

Warsaw, 02-677, Poland
Epic Medical Research
RECRUITING

DeSoto, Texas, 75115, United States
Essence MD Research
RECRUITING

Naples, Florida, 34102, United States
Fukuoka University Hospital_Respiratory Medicine
NOT_YET_RECRUITING

Fukuoka, 814-0180, Japan
Government Siddhartha Medical College & Government General Hospital, Vijayawada
NOT_YET_RECRUITING

Vijayawada, Andhra Pradesh, 520008, India
Guntur Government medical College
WITHDRAWN

Guntur, Andhra Pradesh, 522004,, India
Gyncentrum Sp. z o. o.
NOT_YET_RECRUITING

Warsaw, 00-124, Poland
H.U. Quirónsalud Madrid
RECRUITING

Pozuelo de Alarcón, Madrid, 28223, Spain
Hitit Üniversitesi Çorum Erol Olçok Eğitim ve Araştırma Hastanesi-Göğüs Hastalıkları
RECRUITING

Merkez/Çorum, 19040, Turkey (Türkiye)
Hospital Ramón y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Univ. de Santa María de Lleida
RECRUITING

Lleida, 25198, Spain
Hospital Universitario San Pedro
NOT_YET_RECRUITING

Logroño, 26006, Spain
Hospital Universitario de Araba
RECRUITING

Vitoria-Gasteiz, 01004, Spain
Hospital Universitario de Guadalajara
RECRUITING

Guadalajara, Castille-La Mancha, 19002, Spain
Hospital Vall d'Hebron
NOT_YET_RECRUITING

Barcelona, 08035, Spain
Hospital Vithas Sevilla
RECRUITING

Castilleja de la Cuesta, 41950, Spain
Houston Pulmonary Medicine Associates, PA
RECRUITING

Houston, Texas, 77089, United States
Institut für Diabetesforschung GmbH Münster - Dr. med. Rose
RECRUITING

Münster, 48145, Germany
Instituto de Investigaciones del Sueño
RECRUITING

Madrid, 28036, Spain
Juntendo University Hospital_Cardiovascular Biology And Medicine
NOT_YET_RECRUITING

Tokyo, 113-8431, Japan
KKR Sappro Medical Center_Respiratory Medicine
RECRUITING

Sapporo-shi, Hokkaido, 062-0931, Japan
Krakowski Szpital Specjalistyczny im. Jana Pawla II
WITHDRAWN

Krakow, 31-202, Poland
Kuwamizu Hospital_Internal Medicine
RECRUITING

Kumamoto, 862-0954, Japan
Lillestol Research LLC
RECRUITING

Fargo, North Dakota, 58104, United States
Mater Research - RIO Clinical Trials Unit
NOT_YET_RECRUITING

South Brisbane, Queensland, 4101, Australia
Midland Healthcare & Research Center
NOT_YET_RECRUITING

Lucknow, Uttar Pradesh, 226006, India
Nakamura Clinic_Pulmonology
RECRUITING

Okinawa, 901-2132, Japan
National Institute Of Tuberculosis And Lung Diseases - Instytut Gruźlicy i Chorób Płuc
NOT_YET_RECRUITING

Warsaw, 01-138, Poland
NeuroTrials Research, Inc.
RECRUITING

Atlanta, Georgia, 30328, United States
Nightingale Research
RECRUITING

Adelaide, South Australia, 5000, Australia
Osaka Kaisei Hospital_Sleep Medical Center
RECRUITING

Osaka, 532-0003, Japan
PANSTWOWY INSTYTUT MEDYCZNY MSWiA
NOT_YET_RECRUITING

Warsaw, 02-507, Poland
Palm Beach Research Center
RECRUITING

West Palm Beach, Florida, 33409, United States
Peking University People's Hospital-Endocrinology
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100044, China
Physicians Research Associates
RECRUITING

Lawrenceville, Georgia, 30046, United States
Rainier Clin Res Ctr Inc
RECRUITING

Renton, Washington, 98057, United States
Rajarajeswari Medical College and Hospital
NOT_YET_RECRUITING

Bengaluru, Karnataka, 560074, India
Seattle Clinical Research Center
RECRUITING

Seattle, Washington, 98104, United States
Shenzhen People's Hospital-Sleep Medicine Department
NOT_YET_RECRUITING

Shenzhen, Guangdong, 518020, China
Siteworks GmbH - Prüfzentrum Schleswig | RespiRatio
RECRUITING

Schleswig, 24837, Germany
Siteworks GmbH Bochum
RECRUITING

Bochum, 44787, Germany
Siteworks GmbH Hannover
RECRUITING

Hanover, 30449, Germany
Siteworks GmbH Karlsruhe
RECRUITING

Karlsruhe, 76137, Germany
Sleep Therapy Research Center
RECRUITING

San Antonio, Texas, 78229, United States
T.C. Sağlık Bakanlığı Alaaddin Keykubat Üniversitesi Alanya Eğitim ve Araştırma Hastanesi-Göğüs Hastalıkları
NOT_YET_RECRUITING

Alanya/ Antalya, 07400, Turkey (Türkiye)
Taipei Medical University Hospital
NOT_YET_RECRUITING

Taipei, 110, Taiwan
Taipei Municipal Wan Fang Hospital_Division of Otorhinolaryngology
NOT_YET_RECRUITING

Taipei, 116, Taiwan
The First Affiliated Hospital of Henan University of Science and Technology-Endocrinology
NOT_YET_RECRUITING

Luoyang, Henan, 471003, China
The Second Affiliated Hospital of Nanjing Medical University-Endocrinology
NOT_YET_RECRUITING

Nanjing, Jiangsu, 210011, China
Tianjin Medical University General Hospital-Respiratory
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300052, China
Tokyo Tenshi Hospital_Internal medicine
RECRUITING

Tokyo, 193-0811, Japan
Tokyo-Eki Center-building Clinic_Internal Medicine
NOT_YET_RECRUITING

Tokyo, 103-0027, Japan
Tricoastal Sleep Center
RECRUITING

Sugar Land, Texas, 77478, United States
University of Sunshine Coast - Vitality Village
RECRUITING

Birtinya, Queensland, 4575, Australia
University of Western Australia - Centre for Sleep Science
RECRUITING

Crawley, Western Australia, 6009, Australia
Uniwersytecki Szpital Kliniczny W Poznaniu
NOT_YET_RECRUITING

Poznan, 60-569, Poland
Uniwersyteckie Centrum Kliniczne
NOT_YET_RECRUITING

Gdansk, 80-214, Poland
Vardhaman Mahavir Medical College & Safdarjung Hospital
NOT_YET_RECRUITING

New Delhi, National Capital Territory of Delhi, 110029, India
Weil Cornell Medicine
NOT_YET_RECRUITING

New York, New York, 10021, United States
Wendisch - Dahl Hamburg - DZHW
RECRUITING

Hamburg, 22607, Germany
Woolcock Institute
RECRUITING

Macquarie Park, New South Wales, 2113, Australia
Yashoda Hospital
WITHDRAWN

Hyderabad, Telangana, 500084, India
Yedikule Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi
RECRUITING

Zeytinburnu/İstanbul, 34020, Turkey (Türkiye)
İnönü Üniversitesi Turgut Özal Tıp Merkezi Hastanesi- Göğüs Hastalıkları
RECRUITING

Merkez/Battalgazi/Malatya, 44280, Turkey (Türkiye)
İstanbul İl Sağlik Müdürlüğü Süreyyapaşa Göğüs Hastaliklari Ve Göğüs Cerrahisi Eğitim Ve Araştirma Hastanesi
RECRUITING

Maltepe/İstanbull, 34843, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.

OBESITY OBSTRUCTIVE SLEEP APNOEA OVERWEIGHT