Weekly insulin shot could replace daily injections for millions

NCT ID NCT04880850

Completed Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

Summary

This study tested if a new insulin, injected just once a week, works as well and is as safe as a standard daily insulin for people with type 2 diabetes. Over 580 participants, who were already using multiple daily insulin injections, were randomly assigned to receive either the weekly or daily insulin for 26 weeks. The main goal was to see if the weekly insulin controlled blood sugar levels as effectively as the daily version, while also monitoring for safety issues like low blood sugar.

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Contacts and locations

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Locations

A.O.U. Università Studi della Campania "Luigi Vanvitelli"

Naples, Campania, 80138, Italy
A.O.Universitaria S.ORSOLA-MALPIGHI - U.O.Endocrinologia e Cura

Bologna, 40138, Italy
AM Diabetes And Endocrinology Center

Bartlett, Tennessee, 38133, United States
AMC Community Endocrinology

Albany, New York, 12206, United States
All India Institute of Medical Sciences

New Dehli, New Delhi, 110029, India
Amarillo Med Spec LLP

Amarillo, Texas, 79106, United States
Anaheim Clinical Trials

Anaheim, California, 92801, United States
Arkhangelsk Regional Clinical Hospital

Arkhangelsk, 163045, Russia
Atlanta VA Medical Center

Decatur, Georgia, 30033, United States
Azienda Ospedaliero-Universitaria Renato Dulbecco

Catanzaro, Cz, 88100, Italy
BSES MG hospital

Mumbai, Maharashtra, 400058, India
Bangalore Clinisearch

Bangalore, Karnataka, 560043, India
Baylr Sctt White Rs Inst, Endo

Dallas, Texas, 75226, United States
Belgaum Diabetes Centre

Belagavi, Karnataka, 590001, India
Bethesda Diabetes Research Center en Bethesda ziekenhuis

Hoogeveen, 7909 AA, Netherlands
Brigham & Women's Hospital

Boston, Massachusetts, 02115, United States
CHU Helora - Site Warquignies

Boussu, 7300, Belgium
Capital Clin Res Ctr,LLC

Olympia, Washington, 98502, United States
Centro de Investigacion Medica de Occidente S.C.

Zapopan, Jalisco, 45116, Mexico
Chase Medical Research LLC

Waterbury, Connecticut, 06708, United States
City Clinical Hospital №52

Moscow, 123182, Russia
City Hospital #5

Barnaul, 656045, Russia
Clinical Emergency Sf. Apostol Andrei Hospital

Galati, 800578, Romania
Clinical Trial Res Assoc,Inc

Plantation, Florida, 33324, United States
Clinical Trials Research_Sacramento_0

Sacramento, California, 95821, United States
Cliniques Universitaires Saint-Luc - Serv Endocrinologie - Diabétologie

Brussels, 1200, Belgium
Coastal Metabolic Research Center

Ventura, California, 93003, United States
DCOL Ctr for Clin Res

Longview, Texas, 75605, United States
Diabetes Research Center

Tustin, California, 92780, United States
Diabetes, Thyroid and Endocrine Centre

Jaipur, Rajasthan, 302006, India
Diabetes/Lipid Mgmt & Res Ctr

Huntington Beach, California, 92648, United States
Diablo Clinical Research, Inc.

Walnut Creek, California, 94598, United States
East West Med Res Inst

Honolulu, Hawaii, 96814, United States
Fortis Hospital, Shalimar Bagh, New Delhi

New Delhi, National Capital Territory of Delhi, 110088, India
Futata Tetsuhiro Clinic Meinohama_Internal medicine

Fukuoka-shi, Fukuoka, 819-0006, Japan
Gelre Ziekenhuizen Apeldoorn

Apeldoorn, 7334 DZ, Netherlands
Grant Medical Foundation

Pune, Maharashtra, 411001, India
Hayashi Diabetes Clinic_Internal Medicine and Diabetes Medicine

Chigasaki-shi, Kanagawa, Japan, 253-0044, Japan
Holston Medical Group

Kingsport, Tennessee, 37660, United States
Hospital Universitario Dr. José Eleuterio González_Monterrey

Monterrey, Nuevo León, 64460, Mexico
Ikazia Ziekenhuis

Rotterdam, 3083 AN, Netherlands
Imeldaziekenhuis - Bonheiden - Department of Endocrinology

Bonheiden, 2820, Belgium
Indiana-Armstrong Endocrinology Associates

Indiana, Pennsylvania, 15701, United States
Institutul National De Diabet Nutritie Si Boli Metabolice Prof.Dr.N.Paulescu Bucuresti- Ion Movila

Bucharest, Bucurestii, 020475, Romania
Istituto Scientifico San Raffaele

Milan, MI, 20132, Italy
Jacksonville Ctr For Clin Res

Jacksonville, Florida, 32216, United States
Jefferson City Medical Group, PC

Jefferson City, Missouri, 65109, United States
John Muir Physicians Network

Concord, California, 94520, United States
KSFMU, Inrereginal Clinical Diagnostic center

Kazan', 420010, Russia
Kirov Clinical Hospital #7

Kirov, 610014, Russia
Kurnool Medical Collage

Kurnool, Andhra Pradesh, 518002, India
LLC "Centr Targetnoy Terapii"

Moscow, 125008, Russia
Lifecare Hospital and Research Centre

Bangalore, Karnataka, 560092, India
Limited Law Company "Healthy Family" Medicine Center"

Novosibirsk, 630099, Russia
Limited Liability Company "AriVa-Med"

Kursk, 305016, Russia
Lynn Institute of the Ozarks

Little Rock, Arkansas, 72204, United States
Maastricht Universitair Medisch Centrum

Maastricht, 6229 HX, Netherlands
Manipal Hospital, Hebbal, Bengaluru

Bengaluru, Karnataka, 560 024, India
Mariodiab Clinic SRL

Brasov, 500101, Romania
MassResearch, LLC

Waltham, Massachusetts, 02453, United States
Maulana Azad Medical College

Delhi, New Delhi, 110002, India
Max Super Speciality Hospital, Saket

New Delhi, National Capital Territory of Delhi, 110017, India
Maxima Medisch Centrum

Eindhoven, 5631 BM, Netherlands
MedStar Diabetes Institute

Washington D.C., District of Columbia, 20010, United States
Medanta - The Medicity Multi-Speciality Hospital, Gurugram

Gurgaon, Haryana, 122001, India
Metabolic Research Institute Inc

West Palm Beach, Florida, 33401, United States
Methodist Physicians Clin

Omaha, Nebraska, 68114, United States
Mountain Diabetes & Endocrine Center

Asheville, North Carolina, 28803, United States
Naka Kinen Clinic_Internal medicine

Ibaraki, 311-0113, Japan
Noritake Clinic

Ushiku-shi, Ibaraki, 300-1207, Japan
North Texas Endocrine Center

Dallas, Texas, 75231, United States
Northport VA Medical Center_Northport_0

Northport, New York, 11768, United States
Ochsner Clinic Foundation

New Orleans, Louisiana, 70121, United States
Oregon Health & Science University_Portland_0

Portland, Oregon, 97239, United States
Osvaldo A. Brusco MD PA

Corpus Christi, Texas, 78414, United States
Oyama East Clinic_Internal Medicine

Tochigi, 323-0022, Japan
Palm Research Center Inc-Vegas

Las Vegas, Nevada, 89148, United States
Physician's East Endocrinology

Greenville, North Carolina, 27834, United States
Physicians Research Assoc. LLC

Lawrenceville, Georgia, 30046, United States
Prince Aly Khan Hospital

Mumbai, Maharashtra, 400010, India
Prisma Health-Upstate

Greenville, South Carolina, 29605-4254, United States
Protenium Clinical Research_Hurst

Fort Worth, Texas, 76113, United States
Regional clinical cardiology dispensary

Saratov, 410039, Russia
Renai Medicity

Kochi, Kerala, 682025, India
Rijnstate Ziekenhuis

Arnhem, 6815 AD, Netherlands
S.C. Medcon S.R.L

Buzău, 120203, Romania
S.C.B. Medical College

Cuttack, Odisha, 753007, India
SPb SBHI City Outpatient clinic #37

Saint Petersburg, 191119, Russia
SUNY Upstate Medical University

Syracuse, New York, 13210, United States
Saltzer Medical Group Research

Nampa, Idaho, 83686-6011, United States
Sasaki Internal Medicine

Hokkaido, 062-0007, Japan
Sc Mediab Srl

Târgu Mureş, Mureș County, 540142, Romania
Shimizu Clinic Fusa

Saitama, 336-0967, Japan
Southgate Medical Group, LLP

West Seneca, New York, 14224, United States
Spitalul Judetean de Urgenta Targoviste

Târgovişte, Dâmbovița County, 130083, Romania
St.John's Hospital

Bangalore, Karnataka, 560034, India
Sugimoto Clinic,Internal Medicine

Kitakyusyu-shi, Fukuoka, 800-0222, Japan
Texas Diab & Endo, P.A.

Austin, Texas, 78731, United States
Texas Diabetes & Endocrinology

Austin, Texas, 78749, United States
The Jikei University Hospital Dept of Diabetes, Metabolic

Tokyo, 105-8471, Japan
Tumen State Medical University

Tyumen, Russia, 625023, Russia
UT Southwestern Med Cntr

Dallas, Texas, 75390-9302, United States
UZ Leuven - Endocrinology

Leuven, 3000, Belgium
UZA - UZ Antwerpen - Department of Endocrinology

Edegem, 2650, Belgium
Unidad Biomedica Avanzada Monterrey

Monterrey, Nuevo León, 64460, Mexico
Universita Degli Studi Di Roma La Sapienza - Policlinico Umberto I Medicina Sperimentale

Roma, 00161, Italy
Universitair Medisch Centrum Utrecht

Utrecht, 3584 CX, Netherlands
Università degli Studi G. D'Annunzio

Chieti, 66100, Italy
VA NEB - Western IA Health Stm

Omaha, Nebraska, 68105, United States
Valley Clinical Trials, Inc.

Northridge, California, 91325, United States
Valley Research

Fresno, California, 93720, United States
Vanderbilt Diab Obes Clin Tri

Nashville, Tennessee, 37212, United States
Velocity Clin. Res Valparaiso

Valparaiso, Indiana, 46383, United States
Velocity Clinical Res-Dallas

Dallas, Texas, 75230, United States
WR-ClinSearch, LLC

Chattanooga, Tennessee, 37421, United States
Your Diabetes Endocrine Nutrition Group, Inc.

Mentor, Ohio, 44060, United States

Conditions

Explore the condition pages connected to this study.

DIABETES MELLITUS, TYPE 2