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Warm water may make colonoscopy less painful for older adults

NCT ID NCT07830823

NEW Diagnosis Sponsor: First People's Hospital Of Lin'an District, Hangzhou Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Colonoscopy can be uncomfortable, especially for older adults. This trial compares two ways to expand the colon during the exam, warm water exchange versus standard gas insufflation, each tested with and without anesthesia. Researchers randomly assign 200 participants aged 55 and older to one of four groups. They measure pain scores, time to reach the cecum, and blood levels of inflammatory markers to see which method is safer and more comfortable.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
water exchange colonoscopy, a procedure that uses warm water instead of air to expand the colon during the exam
What this could lead to
If water exchange works better, doctors could offer a more comfortable colonoscopy to older adults, including those who cannot safely receive anesthesia.
What could go wrong
This is a single-center study of 200 people, so the results may not apply everywhere. Pain and inflammatory marker changes are short-term measures and may not reflect how well the procedure detects polyps or cancer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

200 people

The number who actually took part.

Started

Nov 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥ 55 years 2. Indications for colonoscopy 3. Signed informed consent form Exclusion Criteria: 1. History of intestinal surgery 2. Severe intestinal stenosis or obstruction 3. Cognitive impairment that precludes cooperation with assessment

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colonoscopy Colorectal cancer screening

Contacts and locations

Locations

  • Department of Colorectal Surgery, The First People's Hospital of Lin'an District, Hangzhou

    Hangzhou, Zhejiang, 311300, China

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