Can one number judge colonoscopy quality for every patient?
NCT ID NCT05125939
First seen Sep 11, 2026 · Last updated Sep 11, 2026
Summary
Doctors often judge colonoscopy quality by how many screening patients have adenomas found, but that measure leaves out people who get colonoscopies for surveillance or symptoms. This study at multiple hospitals in Taiwan compares the screening-only adenoma detection rate with a broader rate that includes screening, surveillance, and diagnostic colonoscopies. Researchers enroll about 2,700 adults aged 50 and older without high-risk inherited conditions or inflammatory bowel disease. The goal is to see whether the broader measure is a reliable substitute for the screening-only one.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If the broader measure proves reliable, hospitals could track colonoscopy quality with one number instead of separating screening from other reasons, which may make quality reporting simpler and more consistent.
- What could go wrong
- This is an observational comparison, not a test of a treatment, so it cannot improve detection by itself. The findings may not hold in centers with different patient mixes or practices.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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2,707 people
The number who actually took part.
- Started
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Nov 2021
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients aged ≥50 years undergoing screening, surveillance, diagnostic, and FIT+ colonoscopy are eligible for enrollment in this study.
- Ages
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50 to 80 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * consecutive patients aged ≥50 years undergoing colonoscopy are eligible for enrollment. Exclusion Criteria: * high risk family history of colorectal cancer (CRC) e.g., familial adenomatous polyposis, hereditary non-polyposis CRC syndrome, multiple first degree relatives with CRC, or a single first degree relative with CRC at \<60 years * serrated polyposis syndrome * inflammatory bowel disease * colonoscopy to remove a large neoplastic polyps * obstructive lesions of the colon * gastrointestinal bleeding * current participation in other studies * hospitalized patients * mental retardation * pregnancy * refusal to provide a written informed consent.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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E-Da Dachang Hospital
Kaohsiung City, 80784, Taiwan
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E-Da Hospital
Kaohsiung City, 82445, Taiwan
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Evergreen General Hospital
Taoyuan, 320, Taiwan
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Keelung Chang Gung Memorial Hospital
Keelung, 204, Taiwan
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Linkou Chang Gung Memorial Hospital
Taoyuan, 333, Taiwan
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Sepulveda Ambulatory Care Center, VAGLAHS
North Hills, California, 91343, United States
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