Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a sweet syrup replace the unpleasant colonoscopy prep?

NCT ID NCT07787897

Disease control Sponsor: National Institute of Medical Sciences and Nutrition, Salvador Zubiran Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This trial tests whether a low-volume lactulose drink can clean the bowel as well as the standard high-volume polyethylene glycol (PEG) solution before a colonoscopy. Adults aged 45 to 75 scheduled for routine outpatient colonoscopy are randomly assigned to take either lactulose mixed with water or the usual PEG solution, following a low-fiber diet. The study compares bowel cleanliness, polyp detection, patient comfort, and side effects like nausea or bloating. The goal is to see if a smaller, sweeter preparation could make colonoscopy screening more acceptable without compromising quality.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lactulose (a sweet syrup) compared with polyethylene glycol (PEG), a standard bowel-cleansing solution
What this could lead to
If lactulose works as well as PEG, it could offer a more tolerable and lower-volume option for colonoscopy preparation, potentially improving patient comfort and willingness to undergo screening.
What could go wrong
This is a single-center trial, and lactulose may not clean the bowel as effectively as PEG, which could affect polyp detection. Side effects like bloating or discomfort may still occur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

200 people

The number who actually took part.

Started

Jul 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients scheduled for outpatient colonoscopies for colorectal cancer screening Ages 45 to 75 Informed consent form required Exclusion Criteria: Pregnancy Patients with colon resections and/or ileostomies Allergy to the medications studied Intolerance to the oral route Hepatic cirrhosis Ascites Chronic kidney disease on peritoneal dialysis or hemodialysis, decompensated heart disease (ischemic heart disease, congestive heart failure, unstable angina) Inflammatory bowel disease Inability to understand the instructions for bowel preparation Suspected intestinal obstruction or perforation Patients with lower gastrointestinal bleeding History of colon cancer History of inadequate bowel preparation History of polyps in previous colonoscopies Bow preparation intake \<50%

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Colonoscopy are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colonoscopy

Contacts and locations

Locations

  • National Institute of Medical Sciences and Nutrition Salvador Zubiran

    Mexico City, Tlalpan, 14080, Mexico

More trials for these conditions

Other studies related to the condition(s) this trial covers.