Immunotherapy may let some rectal cancer patients ditch surgery
NCT ID NCT04643041
First seen Jan 05, 2026 · Last updated May 16, 2026 · Updated 21 times
Summary
This study looks at whether people with a certain type of rectal cancer (dMMR/MSI-H) can safely avoid surgery if their tumor disappears after immunotherapy. Standard treatments like surgery or chemo can cause lasting side effects, including loss of bowel control or needing a permanent colostomy. The study will follow 47 patients who had a complete response to a PD-1 inhibitor to see if a 'watch and wait' approach is safe and effective.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sun Yatsen University
RECRUITINGGuangzhou, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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