Could a gut bacteria transplant help control type 1 diabetes?
NCT ID NCT06256614
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is testing whether transplanting gut bacteria from healthy donors into people with type 1 diabetes can help control blood sugar and reduce insulin needs. Fifty participants will receive three doses of washed microbiota through the gastrointestinal tract. Researchers will track daily insulin use and time spent in target blood sugar range to see if the treatment is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- washed microbiota from healthy donors
- What this could lead to
- If it works, this could offer a new way to help manage type 1 diabetes by improving blood sugar control and reducing the amount of insulin needed.
- What could go wrong
- This is a small, early real-world study with only 50 participants, so results may not apply to everyone. The treatment involves infusing donor bacteria into the gut, which carries unknown risks and may not provide lasting benefits.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
RECRUITINGNanjing, Jiangsu, 210011, China
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