Could a gut bacteria transplant help control type 1 diabetes?

NCT ID NCT06256614

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether transplanting gut bacteria from healthy donors into people with type 1 diabetes can help control blood sugar and reduce insulin needs. Fifty participants will receive three doses of washed microbiota through the gastrointestinal tract. Researchers will track daily insulin use and time spent in target blood sugar range to see if the treatment is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

washed microbiota from healthy donors

What this could lead to

If it works, this could offer a new way to help manage type 1 diabetes by improving blood sugar control and reducing the amount of insulin needed.

What could go wrong

This is a small, early real-world study with only 50 participants, so results may not apply to everyone. The treatment involves infusing donor bacteria into the gut, which carries unknown risks and may not provide lasting benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypoglycemia Insulin Resistance type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, 210011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••