Heart mapping showdown: which technique stops dangerous rhythms best?

NCT ID NCT06371729

Recruiting now Disease control Sponsor: IRCCS Ospedale San Raffaele Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two methods—DEEP mapping and activation mapping—used during catheter ablation to treat ventricular tachycardia (VT), a fast, dangerous heart rhythm. About 222 adults with an implanted defibrillator and VT will be randomly assigned to one technique. The goal is to see which approach better prevents VT from coming back over 12 months and is easier for doctors to perform.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: catheter ablation guided by DEEP mapping or activation mapping
What this could lead to: If successful, this could identify the better mapping method for VT ablation, potentially reducing repeat procedures and improving long-term heart rhythm control.
What could go wrong: This is a mid-stage trial with 222 participants, so results may not apply to all patients. Both techniques are established, so the difference may be small, and risks like bleeding or heart damage from ablation remain.

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Conditions

The condition(s) this trial relates to.

ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VENTRICULAR TACHYCARDIA

Contacts and locations

Locations

San Raffaele Hospital
RECRUITING

Milan, Lombardy, 20132, Italy

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