Virtual reality may calm colonoscopy jitters without drugs

NCT ID NCT06346171

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether a combination of virtual reality and psychotherapy can help people undergoing colonoscopy without sedation feel less anxious and experience less pain. Participants will be randomly assigned to receive the VR-enhanced psychotherapy, a sham VR distraction, or standard care. The study aims to see if this non-drug approach improves the procedure experience and could encourage more people to get screened for colorectal cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
virtual reality combined with integrative psychotherapy (music therapy, breathing exercises, progressive muscle relaxation, and values discussion)
What this could lead to
If effective, this approach could offer a drug-free way to reduce anxiety and pain during colonoscopy, potentially improving patient experience and screening uptake.
What could go wrong
This is a very small early-stage trial with only 36 participants, so results may not apply broadly. The intervention is complex and may not work for everyone, and some people may experience motion sickness or discomfort with VR.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Pain Pain, Procedural

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Medicine and Pharmacy Grigore T Popa

    Iași, Iaşi, 700115, Romania

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