New drug combo aims to tame tough Crohn's

NCT ID NCT03167437

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This early-phase study tests whether the drug vorinostat is safe and can help control moderate-to-severe Crohn's disease. Participants who respond well may then receive long-term maintenance therapy with another drug, ustekinumab, for up to two years. The goal is to reduce gut inflammation and improve symptoms, but this is not a cure—ongoing treatment is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.