Brain Wave-Guided stimulation may tame tough seizures
NCT ID NCT04693221
First seen Feb 11, 2026 · Last updated May 15, 2026 · Updated 14 times
Summary
This study tests whether adjusting a vagal nerve stimulator based on brain wave patterns (called PLI) can better reduce seizures in people with epilepsy that doesn't respond to medication. About 140 participants with a newly implanted stimulator will have their device settings chosen either by their brain wave readings or by standard methods. The goal is to see if personalized settings lead to fewer seizures per month.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clinical neurophysiology, CHU Dijon
Dijon, France, 21079, France
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Clinical neurophysiology, CHU Lille
Lille, France, 59037, France
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Department of clinical neurophysiology, Hôpital La Timone, APHM
Marseille, France, 13885, France
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Department of functional explorations of the nervous system, CHU
Amiens, France, 80054, France
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Epilepsy neurophysiopathology department, CHU Grenoble
Grenoble, France, 38043, France
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Epileptology Department, CHU Rennes
Rennes, France, 35000, France
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HCL Lyon
Lyon, France, 69003, France
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Hôpital St Joseph St Luc
Lyon, FRA, 69007, France
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Neurology Department, CHU Bordeaux
Bordeaux, France, 33000, France
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Neurology Department, CHU Strasbourg
Strasbourg, France, 67098, France
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Neurology and clinical neurophysiology, CHU Bretonneau
Tours, France, 37044, France
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Neuropediatrics department, CHU Angers
Angers, France, 49933, France
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Neurophysiological explorations, Hôpital Pierre Paul Riquet, Purpan
Toulouse, France, 31059, France
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Neurophysiology Department
Paris, France, 75014, France
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Neurophysiology Department, CHU Rouen
Rouen, France, 76000, France
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Neurosurgery Department, APHP
Paris, France, 75013, France
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Neurosurgery Department, CHRU Nancy
Nancy, France, 54000, France
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Neurosurgery Department, CHU Nantes
Nantes, France, 44093, France
Conditions
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