Keto diet showdown: can extreme Low-Calorie plan beat mediterranean for Long-Term weight loss?
NCT ID NCT05781269
First seen Oct 31, 2025 · Last updated Apr 28, 2026 · Updated 21 times
Summary
This study compares a very-low-calorie ketogenic diet (VLCKD) to a standard Mediterranean diet in 100 adults with severe obesity and metabolic syndrome. The goal is to see which diet leads to better weight loss and improved heart health over 36 months. Participants will be randomly assigned to one of the two diets and monitored for changes in weight, blood sugar, cholesterol, blood pressure, and other health markers.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Istituto Auxologico Italiano
Milan, 20145, Italy
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