Experimental drug tested for Hard-to-Treat bowel disease

NCT ID NCT06137183

Terminated Disease control Sponsor: Genentech, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested an experimental drug called vixarelimab in people with moderate to severe ulcerative colitis who hadn't responded well to other treatments. The trial aimed to see if the drug could reduce bowel inflammation and symptoms over 12 weeks, and then explore longer-term effects. The study was terminated early and involved 79 participants across multiple medical centers.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Advanced Research Institute, Inc.

New Port Richey, Florida, 34653, United States
Allmedica Badania Kliniczne sp. z o.o. sp.k.

Nowy Targ, 34-400, Poland
Atlanta Gastroenterology Associates

Atlanta, Georgia, 30342, United States
Azienda Ospedaliero Universitaria Di Bologna - Policlinico S Orsola Malpighi-Via Massarenti

Bologna, Emilia-Romagna, 40138, Italy
CHU de Nancy-Hopital Brabois Adulte

Vandœuvre-lès-Nancy, 54511, France
CHU de Saint-Etienne - Hopital Nord

Saint-Etienne, 42055, France
Carolina Digestive Diseases

Greenville, North Carolina, 27834, United States
Centro Medico Clinico Quirurgico Especializado en Investigacion

Tlajomulco de Zúñiga, Jalisco, 45645, Mexico
Centro de Estudos Clinicos do Interior Paulista

Jaú, São Paulo, 17201-130, Brazil
Centrum Medyczne Euromedis Sp. z o.o.

Sopot, Pomeranian Voivodeship, 81-756, Poland
Centrum Medyczne UNO-MED-Tarnow

Tarnów, 33-100, Poland
Centrum Zdrowia MDM

Warsaw, 00-635, Poland
China Medical University Hospital

Taichung, 40447, Taiwan
Cliagen Clinica de Atençao em Gastroenterologia, Especialidades e Nutriçao

Salvador, Estado de Bahia, 41500-300, Brazil
Clinical Applications Laboratories, Inc.

San Diego, California, 92103-5639, United States
Clinical Hospital Center Zvezdara

Belgrade, 11000, Serbia
Clinical Trials UMED Sp. z o. o.

?ód?, 92-213, Poland
Delta Gastroenterology & Endoscopy Center

Southaven, Mississippi, 38671, United States
Endohope klinika s. r.o.

Prague, 150 00, Czechia
EuroMediCare Szpital Specjalistyczny z Przychodni? we Wroc?awiu

Wroclaw, Lower Silesian Voivodeship, 54-144, Poland
Evangelismos General Hospital of Athens

Athens, Attica, 106 76, Greece
Facey Medical Foundation - Mission Hills

Mission Hills, California, 91345 1116, United States
Fondazione Policlinico Universitario A Gemelli-Rome

Rome, Lazio, 00168, Italy
Gastro Intestinal Research Institute of Northern Ohio

Westlake, Ohio, 44145, United States
General Hospital Djordje Joanovic - Zrenjanin

Zrenjanin, 23000, Serbia
Henry Ford Health System

Novi, Michigan, 48377, United States
Hepato-Gastroenterologie HK, s.r.o.

Hradec Králové, 500 12, Czechia
Hospital de Clinicas de Porto Alegre HCPA PPDS

Pôrto Alegre, Pará, 90035-903, Brazil
Hôpital L'archet 2

Nice, Alpes-Maritimes, 06202, France
Iatriko Palaiou Falirou

Palaió Fáliro, 175 62, Greece
Inje university Haeundae Paik Hospital

Busan, 48108, South Korea
Istituto Clinico Humanitas

Rozzano, Lombardy, 20089, Italy
Jinhua municipal central hospital

Jinhua, 321000, China
Kaiser Hospital Dia

São José do Rio Preto, São Paulo, 15015-110, Brazil
Kangbuk Samsung Hospital

Seoul, 03181, South Korea
L2 Ip - Instituto de Pesquisas Clinicas Ltda - ME

Brasília, Federal District, 70200-730, Brazil
MZ Badania Slowik Zymla Sp.j.

Knurów, 44-190, Poland
Mayo Clinic - PPDS

Rochester, Minnesota, 55905, United States
Medical Care & Research SA de CV

Mérida, Yucatán, 97070, Mexico
Medical Center Kermed

Bydgoszcz, 85-231, Poland
Military Medical Academy

Belgrade, 11000, Serbia
NZOZ FORMED sp zo.o.

Wadowice, 34-100, Poland
OM Research LLC - Camarillo - ClinEdge - PPDS

Camarillo, California, 93012, United States
Office of Jaroslaw Kierkus, Dr n Med

Otwock, 05-400, Poland
Orlando Gastroenterology, P.A.

Orlando, Florida, 32835, United States
Ospedale San Raffaele S.r.l. - PPDS

Milan, Lombardy, 20132, Italy
Pesquisare Saude

Santo André, São Paulo, 09080-110, Brazil
PlanetMed

Wroc?aw, 52-210, Poland
PreventaMed s.r.o.

Olomouc, 779 00, Czechia
Przychodnia VISTAMED

Wroc?aw, 53-149, Poland
Renmin Hospital of Wuhan University

Wuhan, 430060, China
Sonomed Sp. z o.o.

Szczecin, 71-685, Poland
SurGal Clinic s.r.o.

Brno, 602 00, Czechia
Sylvester Comprehensive Cancer Center

Miami, Florida, 33136, United States
The Catholic University of Korea Daejeon ST. Mary?s Hospital

Daejeon, 34943, South Korea
The First Affiliated Hospital of Nanchang University

Nanchang, China
The First Affiliated Hospital of Ningbo University(Ningbo First Hospital)

Ningbo, 315000, China
The First Affiliated Hospital, Sun Yat-sen University

Guangzhou, 510080, China
The Sixth Affiliated Hospital of Sun Yat-sen University

Guangzhou, 510655, China
Topolowa Medicenter Mrozek & Wspolnicy Spolka Jawna

Krakow, 31-506, Poland
Tyler Research Institute, LLC

Tyler, Texas, 75701, United States
UCLA Clinical and Translational Research Center

Los Angeles, California, 90095, United States
Union Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, 430023, China
University of Utah - Health Sciences Center - PPDS

Salt Lake City, Utah, 84132, United States
Yonsei University Wonju Severance Christian Hospital

Gangwon-do, 26426, South Korea

Conditions

Explore the condition pages connected to this study.

ULCERATIVE COLITIS