Prenatal vitamin d may shield kids from asthma

NCT ID NCT00856947

Ongoing Prevention Sponsor: Copenhagen Studies on Asthma in Childhood Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving mothers high-dose vitamin D (2400 IU daily) from week 24 of pregnancy until one week after birth can prevent asthma symptoms like wheezing in their children. 600 mothers from the ABC cohort in Denmark are participating. The children are followed for several years to see if they develop persistent wheeze or asthma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D3 (cholecalciferol)
What this could lead to: If it works, this could point toward a simple way to reduce asthma risk in children by giving vitamin D to mothers during pregnancy.
What could go wrong: This is an early-phase study, so results are uncertain. The effect may be small or not appear at all, and the high dose might have unknown side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

allergic disease Eczema Infections Respiratory Sounds asthma prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

Locations

Copenhagen University Hospital of Copenhagen

Gentofte Municipality, Gentofte, 2820, Denmark
Næstved Hospital, Pediatric Department

Næstved, Næstved, 4700, Denmark

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