Vitamin c: the surprising new weapon against emergency room pain?

NCT ID NCT06306183

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether vitamin C can reduce pain from recent muscle, bone, or joint injuries in emergency patients. Adults with moderate to severe pain are randomly given vitamin C or a placebo for three days. The goal is to see if this cheap, safe supplement can offer relief and cut down on opioid use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vitamin C (900 mg twice daily for 3 days)

What this could lead to

If it works, this could provide a simple, low-cost, and safe option to manage pain after injuries, reducing the need for opioids.

What could go wrong

This is a small, early-stage trial (204 participants) testing a short-term effect. Vitamin C may not reduce pain significantly, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain Emergencies Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Québec - Université Laval

    NOT_YET_RECRUITING

    Québec, Quebec, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital du Sacre-Coeur de Montreal

    RECRUITING

    Montreal, Quebec, H4J 1C5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôtel-Dieu de Lévis

    NOT_YET_RECRUITING

    Lévis, Quebec, G6V 3Z1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Ottawa Hospital - General and Civic Campus

    NOT_YET_RECRUITING

    Ottawa, Ontario, K1Y 1J8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••