Could a common vitamin boost immunotherapy for melanoma?
NCT ID NCT06377111
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early-phase trial is testing whether taking high-dose vitamin B5 (pantothenic acid) can help standard immunotherapy work better for people with advanced melanoma that cannot be surgically removed. The study includes 12 participants who have not had prior treatment for their advanced cancer. Researchers will measure vitamin B5 levels in the blood and look for signs of immune system changes and tumor response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Vitamin B5 (pantothenic acid, calcium pantothenate)
- What this could lead to
- If it works, this could point toward a simple vitamin supplement that helps immunotherapy work better for advanced melanoma.
- What could go wrong
- This is a very small, early phase 1 trial with only 12 people. It mainly checks if vitamin B5 levels rise in the blood, not whether it actually improves cancer outcomes. Success is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Health Network- Princess Margaret Cancer Centre
Toronto, Ontario, M5G 2M9, Canada
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