New antibody combo aims to boost lung cancer treatment response

NCT ID NCT07098988

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 20 times

Summary

This study tests whether adding the experimental drug visugromab to standard chemotherapy and immunotherapy can shrink tumors better than placebo in people with newly diagnosed metastatic non-squamous non-small cell lung cancer. About 107 adults who have not had prior treatment for advanced disease will receive either visugromab or placebo alongside pembrolizumab, pemetrexed, and carboplatin. The main goal is to see how many participants have their tumors shrink or disappear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • "Sf. Nectarie" Oncology Center, Department of Medical Oncology

    RECRUITING

    Craiova, Dolj, 200542, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cantonal Hospital Saint Gallen, Clinic of Oncology and Hematology

    RECRUITING

    Sankt Gallen, Canton of St. Gallen, 9007, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinica Polisano S.R.L.

    RECRUITING

    Sibiu, 550253, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinics Essen-Mitte

    RECRUITING

    Essen, North Rhine-Westphalia, 45136, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Evangelical Hospital Bethel, Clinic for Internal Medicine, Hematology/Oncology, Palliative Medicine Johannesstift

    RECRUITING

    Bielefeld, North Rhine-Westphalia, 33611, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Foundation Bethanien Moers

    RECRUITING

    Moers, North Rhine-Westphalia, 47441, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fribourg Cantonal Hospital

    RECRUITING

    Fribourg, Canton of Fribourg, 1708, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gral Medical S.R.L. - Oncofort Hospital

    RECRUITING

    Piteşti, 110283, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Großhansdorf Hospital - Clinical Center for Pulmonology and Thoracic Surgery, Department of Thoracic Oncology

    RECRUITING

    Großhansdorf, Schleswig-Holstein, 22927, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital del Mar

    RECRUITING

    Barcelona, Catalonia, 08003, Spain

    Contact Email: •••••@•••••

  • Institute of Romagna for Cancer Research " Dino Amadori" - IRCCS IRST

    RECRUITING

    Meldola, Forli, 47014, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Local Health Unit of Romagna - Santa Maria delle Croci Hospital of Ravenna, Onco-Hematology Department

    RECRUITING

    Ravenna, 48121, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MED-Polonia, Sp. z o.o. (LLC)

    RECRUITING

    Poznan, 60-693, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Longone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cancer Institute Regina Elena, IRCCS

    RECRUITING

    Rome, 00144, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oncology Reference Center

    RECRUITING

    Aviano, 33081, Italy

    Contact Email: •••••@•••••

  • Regional University Hospital of Malaga

    RECRUITING

    Málaga, Andalusia, 29010, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • SC Oncomed SRL, Department of Medical Oncology

    RECRUITING

    Timișoara, +40 () 727 774 974, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START- Rioja

    RECRUITING

    Rioja, La Rioja, 26006, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Specialist Hospital in Prabuty Sp. z o.o. (LLC), Department of Pulmonology

    RECRUITING

    Prabuty, 82-550, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Thorax Clinic Heidelberg

    RECRUITING

    Heidelberg, Baden-Wurttemberg, 69126, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • USC Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Clinic of Navarra - Pamplona

    RECRUITING

    Pamplona, Chartered Community of Navarre, 31008, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital 12 de Octubre

    RECRUITING

    Madrid, Madrid, 28041, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Basel

    RECRUITING

    Basel, Basel, 4031, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Complex of Santiago (CHUS)

    RECRUITING

    Santiago de Compostela, Galicia, 15706, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital HM Sanchinarro

    RECRUITING

    Madrid, Madrid, 28050, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Lucus Augusti (HULA)

    RECRUITING

    Lugo, 27003, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Marques de Valdecilla (HUMV)

    RECRUITING

    Santander, Cantabria, 39008, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Virgen Macarena

    RECRUITING

    Seville, Andalusia, 41009, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Virgen del Rocio (HUVR)

    RECRUITING

    Seville, Andalusia, 41013, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Würzburg

    RECRUITING

    Würzburg, Bavaria, 97080, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital of Jaen

    RECRUITING

    Jaén, Andalusia, 23007, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294-2936, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale Cancer Center

    RECRUITING

    New Haven, Connecticut, 06519, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.