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New drug cocktail aims to shrink lung tumors in Late-Stage trial

NCT ID NCT07246863

Recruiting now Disease control Sponsor: CatalYm GmbH Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times

Summary

This study tests a new drug called visugromab combined with nivolumab and chemotherapy (docetaxel) in people with advanced non-squamous lung cancer that has worsened after initial treatment. About 131 participants will receive different combinations to see if the new drug helps shrink tumors better than standard chemo alone. The goal is to find a more effective second-line treatment option.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADULT SOLID TUMOR METASTATIC NON-SQUAMOUS NON SMALL CELL LUNG CANCER

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Cantonal Hospital Saint Gallen, Clinic of Oncology and Hematology

    RECRUITING

    Sankt Gallen, CH-9007, Switzerland

  • Clinica Polisano S.R.L

    RECRUITING

    Sibiu, Sibiu County, 55023, Romania

  • Clinics Essen-Mitte

    RECRUITING

    Essen, North Rhine-Westphalia, 45136, Germany

  • Clínica Universidad de Navarra

    RECRUITING

    Madrid, Madrid, 28027, Spain

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Evangelical Hospital Bethel, Clinic for Internal Medicine, Hematology/Oncology, Palliative Medicine Johannesstift

    RECRUITING

    Bielefeld, North Rhine-Westphalia, 33611, Germany

  • Foundation Bethanien Moers

    RECRUITING

    Moers, North Rhine-Westphalia, 47441, Germany

  • Hospital Clinic of Barcelona

    RECRUITING

    Barcelona, Catalonia, 08036, Spain

  • Hospital Esslingen GmbH

    RECRUITING

    Esslingen am Neckar, Baden-Wurttemberg, 73730, Germany

  • Institute of Romagna for Cancer Research "Dino Amadori" - IRCCS IRST

    RECRUITING

    Forlì, Emilia-Romagna, 47014, Italy

  • Local Health Unit of Romagna - Santa Maria delle Croci Hospital of Ravenna, Onco-Hematology Department

    RECRUITING

    Ravenna, 48121, Italy

  • MED-Polonia, Sp. z o.o. (LLC)

    RECRUITING

    Poznan, Greater Poland Voivodeship, 60693, Poland

  • NYU Langone Hospital - Long Island

    RECRUITING

    Mineola, New York, 11501, United States

  • NYU Longone Health

    RECRUITING

    New York, New York, 10016, United States

  • National Cancer Institute Regina Elena, IRCCS

    RECRUITING

    Rome, Lazio, 00144, Italy

  • Oncology Reference Center

    RECRUITING

    Aviano, Friuli Venezia Giulia, 33081, Italy

  • Regional University Hospital of Malaga

    RECRUITING

    Málaga, Andalusia, 29010, Spain

  • SC Oncomed SRL

    RECRUITING

    Timișoara, Timiș County, 300239, Romania

  • START- Rioja

    RECRUITING

    Logroño, La Rioja, 26006, Spain

  • Sf. Nectarie Oncology Center

    RECRUITING

    Craiova, Dolj, 200542, Romania

  • Thorax Clinic Heidelberg

    RECRUITING

    Heidelberg, Baden-Wurttemberg, 69126, Germany

  • USC Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

  • University Clinic of Navarra - Pamplona

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • University Hospital 12 de Octubre

    RECRUITING

    Madrid, Madrid, 28041, Spain

  • University Hospital Basel

    RECRUITING

    Basel, 4031, Switzerland

  • University Hospital Complex of Santiago (CHUS)

    RECRUITING

    Santiago de Compostela, Galicia, 15706, Spain

  • University Hospital HM Sanchinarro

    RECRUITING

    Madrid, Madrid, 28050, Spain

  • University Hospital Lucus Augusti (HULA)

    RECRUITING

    Lugo, 27003, Spain

  • University Hospital Virgen del Rocio (HUVR)

    RECRUITING

    Seville, Andalusia, 41013, Spain

  • University Hospital Wuerzburg, Clinic and Polyclinic II for Gastroenterology, Hematology, Internal Oncology, Stem Cell Therapies, Hepatology, Infectiology, Psychosomatics and Rheumatology/ Clinical Immunology

    RECRUITING

    Würzburg, Bavaria, 97080, Germany

  • University Hospital of Girona Dr. Josep Trueta

    RECRUITING

    Girona, Girona, 17007, Spain

  • University Hospital of Jaen

    RECRUITING

    Jaén, Andalusia, 23007, Spain

  • University of Alabama at Birmingham (O'Neal Comprehensive Cancer Center)

    RECRUITING

    Birmingham, Alabama, 35294-3300, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.