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Could belly fat age our cells faster?

NCT ID NCT01525472

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This study investigates whether visceral (belly) fat cells age more quickly than other fat tissue in people with severe obesity, and whether that accelerated aging contributes to conditions like diabetes and heart disease. Researchers will analyze fat samples from about 186 adults undergoing bariatric surgery, looking for signs of cellular aging and inflammation. The goal is to better understand how belly fat becomes harmful and to identify potential targets for future treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the link is confirmed, it could point toward new treatments that slow fat-cell aging and reduce obesity-related diseases like diabetes.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not lead directly to treatments, and findings might not apply to all people with obesity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

186 people

The number who actually took part.

Started

Feb 2012

Finished

Oct 2015

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

hospital center

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 y * Social security insurance * Candidate for bariatric surgery based on criteria established by international experts (BMI\> 40 or\> 35 kg / m² with comorbidities, after failure of multidisciplinary care for a period of at least 1 year) * Patient having signed an informed consent Exclusion criteria * Subject under guardian ship, curator ship or judicial protection. * Subject taking anti-inflammatory and / or non-steroidal drug * Current immunosuppressive therapy or interrupted for less than six months * malignancy or severe inflammatory disease evolving * Positive HIV serology and / or HBV and / or HCV * Current pregnancy * medical or psychiatric contraindication for bariatric surgery

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Conditions

The condition(s) this trial relates to.

morbid obesity Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Morbid obesity

Contacts and locations

Locations

  • Hopital Louis Mourier

    Colombes, 92700, France

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