3D-Printed guides could make jaw surgery more precise

NCT ID NCT05429099

Recruiting now Knowledge-focused Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to rebuild the jaw after oral cancer surgery: standard free-hand surgery versus using 3D-printed guides made from virtual planning. About 420 adults needing jaw reconstruction will be randomly assigned to one method. The main goal is to see which approach leads to better bone healing one year after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Virtual Surgical Planning (3D-printed surgical guides)
What this could lead to: If successful, this could make jaw reconstruction more precise, reducing complications and improving quality of life for oral cancer patients.
What could go wrong: This is a phase 3 trial, but it compares two surgical techniques, not a new drug. The benefit may be small or not apply to all patients, and 3D planning adds cost and time.

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Conditions

The condition(s) this trial relates to.

lip and oral cavity carcinoma Mouth Neoplasms oral cavity cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL CANCER ORAL CAVITY CANCER

Contacts and locations

Locations

Vancouver General Hospital
RECRUITING

Vancouver, British Columbia, V5Z1M9, Canada

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