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Virtual biopsy: a painless MRI scan that spots aggressive prostate cancer

NCT ID NCT04420702

Recruiting now Diagnosis Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether a new type of MRI scan, called Diffusion Basis Spectrum Imaging (DBSI), can accurately detect clinically significant prostate cancer without the need for a needle biopsy. Researchers will compare DBSI results to standard biopsy findings in 500 men — some with suspected cancer and others already on active surveillance. If DBSI proves reliable, it could offer a non-invasive, faster, and more comfortable way to diagnose dangerous prostate cancers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MRI with DBSI analysis
What this could lead to
If successful, this could replace many invasive prostate biopsies with a quick, painless MRI scan, enabling earlier and more accurate detection of dangerous cancers.
What could go wrong
This is a relatively early study comparing DBSI to standard biopsy; the imaging technique may not be accurate enough in all patients, and results need validation in larger, diverse populations.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

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