New combo therapy for diabetic dialysis patients shows promise

NCT ID NCT02176681

Completed Disease control Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding vildagliptin (a diabetes pill) to insulin helps control blood sugar in people with type 2 diabetes who are on hemodialysis. 70 patients were randomly assigned to receive either insulin alone or insulin plus vildagliptin for 12 weeks. The goal was to see if the combination improved blood sugar levels and reduced dangerous lows (hypoglycemia).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vildagliptin (Galvus) added to insulin
What this could lead to: If successful, this could provide a safe and effective way to improve blood sugar control in diabetic patients on dialysis, potentially reducing complications.
What could go wrong: This is a small, early-phase study (70 participants) that only lasted 12 weeks, so results may not apply to all patients. Adding a new drug also carries risks of side effects or interactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HAEMODIALYZED, TYPE 2 DIABETES

Contacts and locations

Locations

AURAL Clinique Sainte Anne

Strasbourg, 67000, France
AURAL Colmar

Colmar, 68000, France
AURAL Mulhouse

Mulhouse, 68070, France
AURAL Strasbourg

Strasbourg, 67200, France
CH d'Amiens

Amiens, 80054, France
CH de Besançon

Besançon, 25030, France
CH de Dijon

Dijon, 21079, France
CH de Mulhouse

Mulhouse, 68070, France
CH de Nancy

Nancy, 54000, France
CH de Valenciennes

Valenciennes, 59300, France
Clinique Sainte Anne

Strasbourg, 67000, France
Hospices civils de Colmar

Colmar, 68024, France
Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France