Blood test may spare thousands from unnecessary brain scans

NCT ID NCT06449183

Completed Diagnosis Sponsor: BioMérieux Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a blood test called VIDAS TBI on 903 adults with mild head injuries in the emergency room. The test measures two brain proteins to see if it can reliably rule out brain damage. If it works well, it could help doctors decide who truly needs a CT scan, saving time and reducing radiation exposure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: VIDAS® TBI blood test (measures GFAP and UCH-L1 proteins)
What this could lead to: If successful, this blood test could help doctors quickly rule out serious brain injury in mild head trauma cases, reducing the need for CT scans and radiation exposure.
What could go wrong: This is a completed study analyzing real-world performance, but the test may not be accurate enough in all settings or populations, and it is not a treatment—it only aids diagnosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Brain Concussion Emergencies traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MILD TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

Mayo Clinic

Rochester, Minnesota, 55905, United States
Orlando Health

Orlando, Florida, 32806, United States
University of Rochester

Rochester, New York, 14627, United States
Washington University

St Louis, Missouri, 63130, United States
Wayne State University

Detroit, Michigan, 48202, United States

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