New combo therapy shows promise for Hard-to-Treat cancers

NCT ID NCT02964013

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 31 times

Summary

This early-phase study tested a new drug called vibostolimab, either alone or combined with pembrolizumab (and sometimes chemotherapy), in 474 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the right dose, and see if the drugs could shrink tumors. The study is complete, and results help guide future research on these combinations.

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