Lung nodule biopsy showdown: which method wins?

NCT ID NCT04250194

Completed Knowledge-focused Sponsor: Vanderbilt-Ingram Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 288 people with a lung nodule to see which biopsy method works better: CT-guided biopsy (needle through the chest wall) or navigation bronchoscopy (a tube through the airways). The goal was to find which approach gives a clear diagnosis with fewer side effects. Results will help guide doctors in choosing the safest and most accurate procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors choose the best biopsy method for lung nodules, improving diagnosis and reducing complications.
What could go wrong: This is a completed study comparing existing procedures, not testing a new treatment. Results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG NODULE

Contacts and locations

Locations

Duke University Medical Center

Durham, North Carolina, 27710, United States
Kootenai Health

Coeur d'Alene, Idaho, 83814, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Rush University Medical Center

Chicago, Illinois, 60612, United States
Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
University of California, San Diego

San Diego, California, 92037, United States
Vanderbilt-Ingram Cancer Center

Nashville, Tennessee, 37232, United States

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