Blood pressure pill shows promise for preserving insulin in newly diagnosed type 1 diabetes

NCT ID NCT04545151

First seen May 20, 2026 · Last updated May 24, 2026 · Updated 1 time

Summary

This study tested whether verapamil, a drug usually used for high blood pressure, could help preserve the body's ability to make insulin in people newly diagnosed with type 1 diabetes. 136 adults took either verapamil or a placebo daily for 12 months. The main goal was to measure changes in C-peptide levels, a marker of insulin production, after a mixed meal. The study is complete, and results will show if verapamil can slow the loss of beta-cell function.

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Contacts and locations

Locations

  • Addenbrokes Hospital

    Cambridge, United Kingdom

  • Bart's Hospital QMUL

    London, United Kingdom

  • Guy's Hospital

    London, United Kingdom

  • HKA Hannover

    Hanover, Germany

  • Institut National de la Santé et de la Recherche Médicale

    Paris, France

  • John Radcliffe Hospital

    Oxford, United Kingdom

  • Katholieke Universiteit Leuven

    Leuven, Belgium

  • Medical University of Graz, Department of Internal Medicine Division of Endocrinology and Metabolism

    Graz, Styria, 8010, Austria

  • NHS Greater Glasgow and Clyde-Queen Elizabeth University Hospital, Department of Diabetes

    Glasgow, United Kingdom

  • OCDEM, John Radcliffe Hospital

    Oxford, United Kingdom

  • Queen Elizabeth Hospital

    Birmingham, United Kingdom

  • Queens Medical Centre

    Nottingham, United Kingdom

  • Royal Hallamshire Hospital

    Sheffield, United Kingdom

  • Singleton Hospital

    Swansea, United Kingdom

  • Southmead Hospital

    Bristol, United Kingdom

  • Universitair Ziekenhuis Antwerpen

    Edegem, Belgium

  • Universitair Ziekenhuis Brussel

    Brussels, Belgium

  • University Hospital of Wales

    Cardiff, United Kingdom

  • Università Vita-Salute San Raffaele

    Milan, Italy

  • Università degli Studi di Siena

    Siena, Italy

  • Universität Ulm

    Ulm, Germany

  • Université Libre de Bruxelles/ Hôpital Erasme

    Brussels, Belgium

Conditions

Explore the condition pages connected to this study.