Can a pill tame a common blood cancer in the real world?
NCT ID NCT03415035
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This study follows about 269 people with chronic lymphocytic leukemia (CLL) who are starting venetoclax, a targeted pill. Researchers will track how well the drug shrinks or controls the cancer over the first year, and how long it takes before patients need another treatment. The goal is to see if venetoclax works as well in routine medical care as it did in earlier clinical trials.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- venetoclax
- What this could lead to
- If successful, this study could confirm that venetoclax works well outside of clinical trials, helping doctors better understand its real-world benefits for CLL patients.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be influenced by patient selection or other treatments. It does not test a new drug or compare venetoclax to other options.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AP-HP - Hopital Bicetre /ID# 170747
Le Kremlin-Bicêtre, Paris, 94270, France
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CH Annecy Genevois - Site Annecy /ID# 200826
Epagny Metz Tessy, 74370, France
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CH Bretagne Atlantique /ID# 200191
Vannes, Morbihan, 56017, France
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CH CARCASSONNE - Antoine Gayraud /ID# 202530
Carcassonne, Aude, 11000, France
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CH Cannes - les Broussailles /ID# 201108
Cannes, Alpes-Maritimes, 06414, France
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CH Libourne - Hopital Robert Boulin /ID# 170739
Libourne, 33500, France
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CH Mont de MARSAN /ID# 169955
Mont-de-Marsan, 40024, France
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CH Princesse Grace /ID# 200196
Monaco, 98000, France
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CH Périgueux /ID# 169458
Périgueux, 24019, France
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CH Roubaix - Hopital Victor Provo /ID# 170909
Roubaix, Hauts-de-France, 59100, France
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CH Saint-Brieuc /ID# 171076
Saint-Brieuc, 22000, France
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CH Victor Dupouy /ID# 169946
Argenteuil, 95100, France
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CH William Morey /ID# 169939
Chalon-sur-Saône, 71321, France
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CH de Saint-Malo - Hôpital Broussais /ID# 169935
St-Malo, Ille-et-Vilaine, 35400, France
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CH de la Haute-Saône - Vesoul /ID# 205150
Vesoul, Bourgogne-Franche-Comté, 70014, France
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CHI POISSY - Saint-Germain-en-Laye /ID# 169966
Saint-Germain-en-Laye, Yvelines, 78100, France
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CHR Metz-Thionville - Hopital Bel-Air /ID# 170722
Thionville, Moselle, 57100, France
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CHRU Tours - Hopital Bretonneau /ID# 169469
Tours, Indre-et-Loire, 37044, France
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CHRU de Brest - Hopital Morvan /ID# 169457
Brest, 29200, France
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CHU Amiens-Picardie Site Sud /ID# 170724
Amiens, Somme, 80054, France
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CHU Clermont-Ferrand /ID# 170736
Clermont, Auvergne-Rhône-Alpes, 63100, France
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CHU Grenoble - Hopital Michallon /ID# 170741
La Tronche, Isere, 38700, France
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CHU Limoges - Dupuytren 1 /ID# 200193
Limoges, Franche-Comte, 87042, France
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CHU Montpellier - Hopital Saint Eloi /ID# 200192
Montpellier, Herault, 34295, France
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CHU Poitiers - La miletrie /ID# 169470
Poitiers, Vienne, 86000, France
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CHU Reims - Hôpital Robert Debre /ID# 170917
Reims, Marne, 51092, France
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CHU de CAEN - Hopital de la Cote de Nacre /ID# 169941
Caen, Calvados, 14033, France
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CHU de RENNES /ID# 169944
Rennes, Brittany Region, 35033, France
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Centre De Lutte Contre Le Cancer - Centre Henri Becquerel Normandie Rouen /ID# 169948
Rouen, Seine-Maritime, 76038, France
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Centre Hospitalier Regional Universitaire de Besancon - Hopital Jean Minjoz /ID# 170721
Besançon, Doubs, 25000, France
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Centre Hospitalier Regional Universitaire de Nancy - Hopitaux de Brabois /ID# 170855
Vandœuvre-lès-Nancy, Meurthe-et-Moselle, 54511, France
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Centre Hospitalier Régional d'Orléans - Hôpital de la Source /ID# 169453
Orléans, 45067, France
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Centre Hospitalier de CHOLET /ID# 171215
Cholet, 49300, France
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Centre Hospitalier de Cornouaille /ID# 169937
Quimper, Finistere, 29000, France
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Centre Hospitalier de Perpignan /ID# 170743
Perpignan, 66000, France
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Centre Hospitalier de Versailles André Mignot /ID# 169950
Le Chesnay, 78150, France
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Centre Hospitalier de la Cote Basque /ID# 170735
Bayonne, Pyrenees-Atlantiques, 64100, France
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Centre Hospitalier du Mans /ID# 169451
Le Mans, Sarthe, 72037, France
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Centre Joseph BELOT /ID# 170853
Désertines, 03030, France
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Centre Leon Berard /ID# 170018
Lyon, Rhone, 69373, France
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Ch Agen /Id# 170742
Agen, 47923, France
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Ch Blois /Id# 170727
Blois, 41016, France
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Ch Mulhouse /Id# 170726
Mulhouse, 68100, France
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Clinique Pole santé République /ID# 204658
Clermont-Ferrand, Auvergne, 63050, France
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Clinique Victor Hugo /ID# 169973
Le Mans, Sarthe, 72000, France
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Clinique de la Sauvegarde /ID# 169904
Lyon, 69009, France
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Hopital Avicenne - APHP /ID# 169940
Bobigny, Île-de-France Region, 93000, France
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Hopital Nord Franche Comté /ID# 170744
Trévenans, 90400, France
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Hopital Pitie Salpetriere /ID# 169974
Paris, Île-de-France Region, 75013, France
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Hopital Prive Sevigne /Id# 170718
Cesson-Sévigné, 35510, France
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Hopital Saint Vincent de Paul /ID# 169956
Lille, 59020, France
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Hopital Saint-Louis /ID# 170856
Paris, 75010, France
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Hopital d'Instruction des Armées PERCY /ID# 170740
Clamart, 92141, France
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Hopital de Melun /ID# 202569
Melun, Seine-et-Marne, 77011, France
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Hopital de la Conception /ID# 201981
Marseille, Provence-Alpes-Côte d'Azur Region, 13005, France
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IUCT Oncopole /ID# 170749
Toulouse, Occitanie, 31059, France
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Institut Bergonie /ID# 170746
Bordeaux, Gironde, 33000, France
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Institut Gustave Roussy /ID# 202436
Villejuif, Val-de-Marne, 94805, France
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Medipole de Savoie /ID# 169454
Challes-les-Eaux, 73190, France
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Polyclinique le LANGUEDOC /ID# 169925
Narbonne, 11100, France
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