Experimental combo targets tough leukemia in early trial

NCT ID NCT03844815

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 24 times

Summary

This early-phase study tests the safety of combining the experimental drug venetoclax with a 10-day course of decitabine in adults with high-risk acute myeloid leukemia (AML). The 26 participants have AML that is relapsed, resistant, or has certain genetic markers. The main goal is to find the best dose and see how tolerable the combination is.

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Contacts and locations

Locations

  • University Of Chicago Medicine Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.