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Real-World study checks how well venetoclax works for AML patients

NCT ID NCT05215639

Completed Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how well the drug Venetoclax works for adults with acute myeloid leukemia (AML) who are not healthy enough for intensive chemotherapy. About 120 patients in Switzerland and Austria took Venetoclax pills daily as part of their normal care. Researchers tracked survival and remission rates over 24 months to see how effective the treatment is in real-world settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Venetoclax (a targeted cancer drug taken as a pill)
What this could lead to
If successful, this study could confirm that Venetoclax is a good treatment option for AML patients who cannot tolerate intensive chemotherapy.
What could go wrong
This is an observational study, not a controlled trial, so results may be less reliable. It only included patients in Switzerland and Austria, so findings may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE MYELOID LEUKEMIA

Contacts and locations

Locations

  • Duplicate_Universitätsspital Basel /ID# 256509

    Basel, Canton of Basel-City, 4031, Switzerland

  • EOC Ospedale Regionale di Bellinzona e Valli /ID# 240663

    Bellinzona, Canton Ticino, 6500, Switzerland

  • Hanusch Krankenhaus /ID# 247282

    Vienna, 1140, Austria

  • Hirslanden Klinik /ID# 239239

    Zurich, Canton of Zurich, 8032, Switzerland

  • Hôpital de Nyon /ID# 240720

    Nyon, 1260, Switzerland

  • Hôpital du Chablais, Rennaz /ID# 241895

    Rennaz, Canton of Vaud, 1847, Switzerland

  • Inselspital, Universitaetsspital Bern /ID# 239241

    Bern, 3010, Switzerland

  • KSW Kantonsspital Winterthur /ID# 239852

    Winterthur, Canton of Zurich, 8400, Switzerland

  • Kantonsspital Aarau AG /ID# 251598

    Aarau, Canton of Aargau, 5001, Switzerland

  • Kantonsspital Baden /ID# 241896

    Baden, Canton of Aargau, 5404, Switzerland

  • Kantonsspital St. Gallen /ID# 239233

    Sankt Gallen, Canton of St. Gallen, 9007, Switzerland

  • Klinik Ottakring /ID# 247285

    Vienna, State of Vienna, 1160, Austria

  • Klinikum Klagenfurt am Wörthersee /ID# 247304

    Klagenfurt, Carinthia, 9020, Austria

  • Krankenhaus der Barmherzigen Brueder Graz /ID# 254121

    Graz, Styria, 8020, Austria

  • Landeskrankenhaus Hochsteiermark, Standort Leoben /ID# 254174

    Leoben, Styria, 8700, Austria

  • Luzerner Kantonsspital /ID# 239242

    Lucerne, Canton of Lucerne, 6000, Switzerland

  • Ordensklinikum Linz GmbH Elisabethinen /ID# 247284

    Linz, Upper Austria, 4010, Austria

  • Spitalzentrum Oberwallis /ID# 241897

    Brig, Valais, 3900, Switzerland

  • Universitaetsklinikum St. Poelten /ID# 247283

    Sankt Pölten, Lower Austria, 3100, Austria

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