New hope for kids with severe bowel disease

NCT ID NCT04779307

Completed Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

Summary

This study tested a drug called vedolizumab as a long-term treatment for children and teenagers with moderate to severe ulcerative colitis, a painful bowel disease. The goal was to see if regular infusions of the drug could help patients achieve and maintain remission, meaning their symptoms go away and their gut looks healthy. The trial involved about 120 young patients who had not responded well to other standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AOU dell'Universita degli Studi della Campania Luigi Vanvitelli - Piazza Luigi Miraglia, 2

Naples, 280138, Italy
Advocate Children's Hospital Park Ridge

Park Ridge, Illinois, 60068, United States
Attikon University General Hospital

Chaïdári, Attica, 124 62, Greece
Azienda Ospedaliera Universitaria Federico II

Naples, Campania, 80131, Italy
Azienda Ospedaliera Universitaria Policlinico Umberto I - Universita di Roma La Sapienza

Rome, Lazio, 00161, Italy
Azienda Ospedaliero Universitaria A Meyer - INCIPIT - PIN

Florence, Tuscany, 50139, Italy
Azienda USL di Bologna

Bologna, Emilia-Romagna, 40133, Italy
Beijing Children's Hospital, Capital Medical University - PIN

Beijing, Beijing Municipality, 100045, China
Birmingham Women's and Children's NHS Foundation Trust

Birmingham, West Midlands, B4 6NH, United Kingdom
Borsod-Abauj-Zemplen Varmegyei Kozponti Korhaz es Egyetemi Oktatokorhaz

Miskolc, 3526, Hungary
Boston Children's Hospital

Boston, Massachusetts, 02115, United States
British Columbia Children's Hospital

Vancouver, British Columbia, V6H 3V4, Canada
Carilion Children's Tanglewood Center

Roanoke, Virginia, 24013-2253, United States
Carmel Medical Center

Haifa, 3436212, Israel
Children's Hospital "Agia Sofia"

Athens, Attica, 115 27, Greece
Children's Hospital at Westmead

Westmead, New South Wales, 2145, Australia
Children's Hospital of Fudan University

Shanghai, Shanghai Municipality, 201102, China
Childrens Center For Digestive Healthcare

Atlanta, Georgia, 30318-4833, United States
Clinexpert Gyogycentrum

Budapest, 1033, Hungary
Fondazione IRCCS San Gerardo dei Tintori - ASST di Monza A. O. San Gerardo

Monza, Monza E Brianza, 20900, Italy
Gachon University Gil Medical Center

Seoul, Incheon Gwang'yeogsi, 3080, South Korea
Gornoslaskie Centrum Zdrowia Dziecka Im. Sw. Jana Pawla II Spsk Nr 6 Sum W Katowicach

Katowice, Silesian Voivodeship, 40-752, Poland
Goryeb Children's Hospital

Morristown, New Jersey, 07960-6136, United States
Great Ormond Street Hospital

London, London, City of, WC1N 3JH, United Kingdom
Hadassah Medical Center - PPDS

Jerusalem, Jerusalem, 91120, Israel
Henan Children's Hospital Zhengzhou Children's Hospital

Zhengzhou, Henan, 450000, China
Instytut 'Pomnik - Centrum Zdrowia Dziecka'

Warsaw, Masovian Voivodeship, 04-736, Poland
Instytut Centrum Zdrowia Matki Polki

Lodz, Łódź Voivodeship, 93-338, Poland
Ippokratio General Hospital of Thessaloniki

Thessaloniki, 546 42, Greece
Japanese Red Cross Kumamoto Hospital

Kumamoto, 861-8520, Japan
Juntendo University Hospital

Bunkyo-Ku, Tokyo, 113-8431, Japan
Klinika Za Djecje Bolesti Zagreb

Zagreb, City of Zagreb, 10000, Croatia
Korczowski Bartosz, Gabinet Lekarski

Rzeszów, Podkarpackie Voivodeship, 35-302, Poland
Kurume University Hospital

Kurume, Hukuoka, 830-0011, Japan
Kyungpook National University Chilgok Hospital

Daegu, Daegu Gwang'yeogsi, 41404, South Korea
London Health Sciences Centre

London, Ontario, N6A 5W9, Canada
MNGI Digestive Health PA-Plymouth

Minneapolis, Minnesota, 55413, United States
Mayo Clinic - PIN

Rochester, Minnesota, 55905-0001, United States
Monash Health, Monash Medical Centre

Clayton, Victoria, 3168, Australia
National Center for Child Health and Development

Setagaya-ku, Tokyo, 157-8535, Japan
Noahs Ark Childrens Hospital for Wales

Cardiff, CF14 4XW, United Kingdom
Phoenix Childrens Hospital -1919 E Thompson Rd

Phoenix, Arizona, 85016-7710, United States
Queensland Childrens Hospital

South Brisbane, Queensland, 4101, Australia
Rady Childrens Hospital San Diego - PIN

San Diego, California, 92123, United States
Rambam Medical Center - PPDS

Haifa, 31096, Israel
Royal Children's Hospital Melbourne - PIN

Parkville, Victoria, 3052, Australia
SPZOZ Centralny Szpital Kliniczny UM w Lodzi - ul. Pomorska 251

Lodz, Łódź Voivodeship, 91-738, Poland
Saitama Children's Medical Center

Saitama, 330-8777, Japan
Samsung Medical Center

Seoul, Seoul Teugbyeolsi, 06351, South Korea
Schneider Childrens Medical Center of Israel Petah Tikvah PIN

Petah Tikva, 49100, Israel
Semmelweis Egyetem

Budapest, 1085, Hungary
Seoul National University Hospital

Seoul, Seoul Teugbyeolsi, 21565, South Korea
Shaare Zedek Medical Center

Jerusalem, Jerusalem, 91031, Israel
Tel Aviv Sourasky Medical Center

Tel Aviv, 64239, Israel
Texas Childrens Hospital West Campus

Houston, Texas, 77030-2358, United States
The Children's Hospital Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310003, China
The Royal London Hospital

London, London, City of, E1 1BB, United Kingdom
Twoja Przychodnia SCM

Szczecin, West Pomeranian Voivodeship, 71-434, Poland
UPMC Children's Hospital of Pittsburgh-120 Lytton Ave

Pittsburgh, Pennsylvania, 15224-1334, United States
UZ Antwerpen

Edegem, Antwerpen, 2650, Belgium
Universitair Ziekenhuis Brussel - PIN

Jette, Brussels Capital, 1090, Belgium
Universitaire Ziekenhuizen(UZ)Leuven-Campus Gasthuisberg

Leuven, Vlaams Brabant, 3000, Belgium
University of Alberta Hospital

Edmonton, Alberta, T6G 2S2, Canada
Uniwersytecki Szpital Dzieciecy

Krakow, Lesser Poland Voivodeship, 30-663, Poland
WIP Warsaw IBD Point Profesor Kierkus

Warsaw, Masovian Voivodeship, 00-728, Poland

Conditions

Explore the condition pages connected to this study.

COLITIS, ULCERATIVE